SCHEMBL4604967

SCHEMBL4604967

CCCc1ncc(N)cc1N

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.35
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 2/20 0.35
USP2 O75604 2/20 0.35
TP53 P04637 2/20 0.35
GAA P10253 2/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 2/20 0.35
ATM Q13315 2/20 0.35
CASP1 P29466 1/20 0.35
HTT P42858 1/20 0.35
CASP7 P55210 1/20 0.35
HSP90AA1 P07900 1/20 0.35
RAB9A P51151 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
HSD17B10 Q99714 2/20 0.34
NPC1 O15118 2/20 0.34
HPGD P15428 1/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9673509 0.83 NOS3 (0.36) KDM4EALDH1A1MEN1USP2TP53
SCHEMBL19171969 0.76 HTT (0.43) KDM4EALDH1A1MEN1GAAKMT2A
SCHEMBL21433001 0.76 AGBL2 (0.44) KDM4EALDH1A1MAPTKMT2APOLB
SCHEMBL11243532 0.72 NTRK1 (0.38) KDM4EALDH1A1MEN1USP2GAA
SCHEMBL23245930 0.71 DHFR (0.38) KDM4EALDH1A1MEN1USP2GAA
SCHEMBL9435816 0.70
SCHEMBL21988047 0.69 RAB9A (0.37) KDM4EALDH1A1MEN1USP2TP53
SCHEMBL30279707 0.69 RAB9A (0.37) KDM4EALDH1A1MEN1USP2TP53
SCHEMBL1982074 0.69 MAPK8 (0.36) KDM4EALDH1A1GAAMAPTHTT
SCHEMBL25198432 0.69 NOS2 (0.37) KDM4EALDH1A1MEN1USP2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1670423-B1 DYE-CONTAINING PELLETS FOR DYEING KERATIN FIBRES WELLA AG (DE) 2008-10-08 EP claimed
EP-0166100-B1 OXIDATION HAIR-DYEING COMPOSITION BASED ON A LOW-VISCOSITY CARRIER Wella Aktiengesellschaft (DE) 1989-01-11 EP claimed
US-4725282-A LOW VISCOSITY; STORAGE STABILITY WELLA AKTIENGESELLSCHAFT (DE) 1988-02-16 US claimed
EP-1660022-B1 AGENT FOR COLOURING KERATIN FIBRES HFC PRESTIGE INT HOLDING SWITZERLAND S A R L (CH) 2017-04-12 EP disclosed
EP-1371353-B1 Thickened cationic cosmetic composition comprising inulin WELLA AG (DE) 2008-08-06 EP disclosed
EP-1915984-A1 Dark coloured azo dyes Wella Aktiengesellschaft (DE) 2008-04-30 EP disclosed
EP-1805266-A1 CATIONIC AZOAZINIC DYES AND COOLANTS CONTAINING SAID COMPOUNDS Wella Aktiengesellschaft (DE) 2007-07-11 EP disclosed
EP-1804921-A1 COLOURING AGENTS CONTAINING CATIONIC INDAZOLINE-THIAZOLAZO DYES Wella Aktiengesellschaft (DE) 2007-07-11 EP disclosed
EP-1771226-A1 MULTICOMPONENT KIT AND METHOD FOR DYEING KERATIN FIBRES Wella Aktiengesellschaft (DE) 2007-04-11 EP disclosed
EP-1555986-B1 USE OF NATIVE ZEIN FOR IMPROVING THE CONDITION OF HAIR, AND CORRESPONDING AGENT WELLA AG (DE) 2007-03-14 EP disclosed
EP-1761239-A1 CATIONIC QUINOXALINE THIAZOLE AZO DYE-CONTAINING COLORANTS Wella Aktiengesellschaft (DE) 2007-03-14 EP disclosed
EP-0650718-B1 Hair oxidation composition based on a creamy carrier and a preparation constituted by a polymer and an oxydation hair dye and process for an oxidation hair dyeing WELLA AG (DE) 1999-03-24 EP disclosed
EP-0485539-B2 OXIDATIVE HAIR DYES CONSISTING OF AN EMULSIFIED DYE CARRIER SUBSTANCE AND AN EMULSIFIED COMPOSITION CONTAINING AN OXIDIZING AGENT AND PROCESS FOR OXIDATIVE DYEING OF HAIR WELLA AG (DE) 1998-06-24 EP disclosed
EP-0485539-B1 OXIDATIVE HAIR DYES CONSISTING OF AN EMULSIFIED DYE CARRIER SUBSTANCE AND AN EMULSIFIED COMPOSITION CONTAINING AN OXIDIZING AGENT AND PROCESS FOR OXIDATIVE DYEING OF HAIR WELLA AG (DE) 1995-10-11 EP disclosed
EP-0650718-A1 Hair oxidation composition based on a creamy carrier and a preparation constituted by a polymer and an oxydation hair dye and process for an oxidation hair dyeing Wella Aktiengesellschaft (DE) 1995-05-03 EP disclosed
EP-0485539-A1 OXIDATIVE HAIR DYES CONSISTING OF AN EMULSIFIED DYE CARRIER SUBSTANCE AND AN EMULSIFIED COMPOSITION CONTAINING AN OXIDIZING AGENT AND PROCESS FOR OXIDATIVE DYEING OF HAIR. WELLA AG (DE) 1992-05-20 EP disclosed
WO-1991018582-A1 OXIDATIVE HAIR DYES CONSISTING OF AN EMULSIFIED DYE CARRIER SUBSTANCE AND AN EMULSIFIED COMPOSITION CONTAINING AN OXIDIZING AGENT AND PROCESS FOR OXIDATIVE DYEING OF HAIR WELLA AKTIENGESELLSCHAFT (DE) 1991-12-12 WO disclosed
US-4725282-A LOW VISCOSITY; STORAGE STABILITY WELLA AKTIENGESELLSCHAFT (DE) 1988-02-16 US disclosed
WO-1986000223-A1 HAIR COLOURING AGENT BASED ON A LOW-VISCOSITY CARRIER WELLA AKTIENGESELLSCHAFT (DE) 1986-01-16 WO disclosed
EP-0166100-A1 Oxidation hair-dyeing composition based on a low-viscosity carrier Wella Aktiengesellschaft (DE) 1986-01-02 EP disclosed