Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.38 |
| ▸ | LATS1 | O95835 | 1/20 | 0.37 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166433 | 0.98 | S1PR2 (0.41) | NPSR1S1PR2LMNASMN1; SMN2TLR8 | |
| SCHEMBL6203304 | 0.76 | UTS2R (0.44) | NPSR1S1PR2LMNASMN1; SMN2TLR8 | |
| SCHEMBL6204833 | 0.73 | CCR4 (0.42) | NPSR1S1PR2LMNASMN1; SMN2TLR8 | |
| SCHEMBL6166421 | 0.70 | CRHR1 (0.49) | — | |
| SCHEMBL6168059 | 0.70 | TLR8 (0.46) | NPSR1S1PR2LMNASMN1; SMN2TLR8 | |
| SCHEMBL6165652 | 0.70 | TLR8 (0.41) | NPSR1S1PR2LMNASMN1; SMN2TLR8 | |
| SCHEMBL6167497 | 0.70 | TLR8 (0.40) | TLR8TLR7HCAR3CYP2D6UTS2R | |
| SCHEMBL1937548 | 0.69 | STK17A (0.54) | NPSR1S1PR2LMNASMN1; SMN2TLR8 | |
| SCHEMBL6168023 | 0.69 | KDM4E (0.40) | NPSR1S1PR2LMNASMN1; SMN2TLR8 | |
| SCHEMBL251411 | 0.68 | MAPKAPK2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499599-A1 | SUBSTITUTED PYRAZINE DERIVATIVES | Pharmacia & Upjohn Company LLC (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003091225-A1 | SUBSTITUTED PYRAZINE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2003-11-06 | — | — | WO | disclosed |