SCHEMBL20009938

SCHEMBL20009938

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccc5[nH]c6ccc(-c7ccc(-c8ccncc8)nc7)cc6c5c4)n3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MKNK1 Q9BUB5 1/20 0.47
PIK3CA P42336 1/20 0.40
GABRA1 P14867 2/20 0.40
GABRG2 P18507 2/20 0.40
GABRB3 P28472 2/20 0.40
GABRA5 P31644 2/20 0.40
GABRA3 P34903 2/20 0.40
HPGDS O60760 2/20 0.40
MAPK10 P53779 1/20 0.40
IMPDH2 P12268 1/20 0.40
GABRA2 P47869 1/20 0.39
GABRA6 Q16445 1/20 0.39
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
PDGFRB P09619 1/20 0.39
PDGFRA P16234 1/20 0.39
WNT3A P56704 1/20 0.39
MAPK13 O15264 1/20 0.39
RAF1 P04049 1/20 0.39
MAPK12 P53778 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20009872 0.99 MKNK1 (0.45) MKNK1PIK3CAGABRA1GABRG2GABRB3
SCHEMBL20010077 0.96 MKNK1 (0.45) MKNK1PIK3CAGABRA1GABRG2GABRB3
SCHEMBL20010279 0.96 MKNK1 (0.45) MKNK1PIK3CAGABRA1GABRG2GABRB3
SCHEMBL20009913 0.89 TLR8 (0.46) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL20009907 0.88 TLR8 (0.44) HPGDSCYP11B1CYP11B2MAPT
SCHEMBL20009871 0.88 TLR8 (0.47) HPGDSCYP11B1CYP11B2MAPT
SCHEMBL20009965 0.87 TLR8 (0.45) HPGDSCYP11B1CYP11B2MAPT
SCHEMBL20010293 0.87 HPGDS (0.48) MKNK1GABRA1GABRG2GABRB3GABRA5
SCHEMBL20010045 0.86 PIK3CA (0.43) MKNK1PIK3CAGABRA1GABRG2GABRB3
SCHEMBL20010191 0.86 WNT3A (0.46) PIK3CAGABRA1GABRG2GABRB3GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210320261-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2021-10-14 US disclosed
US-11081648-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD. (KR) 2021-08-03 US disclosed
US-10468605-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD. (KR) 2019-11-05 US disclosed
US-20180090686-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-03-29 US disclosed
US-20180090686-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180090686-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME OCIAD1, OCIAD2, AOX1 MKNK1 3370/4885PIK3CA 2849/4885GABRA1 2019/4885
US-20210320261-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME OCIAD1, OCIAD2, AOX1 MKNK1 3381/4885PIK3CA 2892/4885GABRA1 2074/4885
US-10468605-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same OCIAD1, OCIAD2, AOX1 MKNK1 3370/4885PIK3CA 2849/4885GABRA1 2019/4885
US-11081648-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same OCIAD1, OCIAD2, AOX1 MKNK1 3370/4885PIK3CA 2849/4885GABRA1 2019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.