SCHEMBL20010045

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20010071	0.99	GABRA1 (0.43)	PIK3CAGABRA1GABRG2GABRB3GABRA5
	SCHEMBL20010240	0.96	MAPK10 (0.43)	PIK3CAGABRA1GABRG2GABRB3GABRA5
	SCHEMBL20010203	0.96	MAPK10 (0.43)	PIK3CAGABRA1GABRG2GABRB3GABRA5
	SCHEMBL20010097	0.90	PDGFRB (0.44)	PIK3CAGABRA1GABRG2GABRB3GABRA5
	SCHEMBL17299035	0.89	HSD17B1 (0.45)	PIK3CACYP11B1CYP11B2DHODHMAPT
	SCHEMBL20010191	0.89	WNT3A (0.46)	PIK3CAGABRA1GABRG2GABRB3GABRA5
	SCHEMBL20009969	0.89	WNT3A (0.46)	PIK3CAGABRA1GABRG2GABRB3GABRA5
	SCHEMBL20010155	0.89	WNT3A (0.46)	PIK3CAGABRA1GABRG2GABRB3GABRA5
	SCHEMBL20009987	0.89	WNT3A (0.46)	PIK3CAGABRA1GABRG2GABRB3GABRA5
	SCHEMBL20010202	0.89	WNT3A (0.46)	PIK3CAGABRA1GABRG2GABRB3GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.