SCHEMBL20010071

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20010045	0.99	PIK3CA (0.43)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL20010203	0.95	MAPK10 (0.43)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL20010240	0.95	MAPK10 (0.43)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL17299035	0.91	HSD17B1 (0.45)	CYP11B1CYP11B2MEN1KMT2AMAPT
	SCHEMBL20009867	0.90	GABRA1 (0.43)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL20009959	0.89	GABRA1 (0.47)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL20009874	0.89	GABRA1 (0.47)	GABRA1GABRG2GABRB3GABRA5GABRA3
	SCHEMBL17299034	0.89	MEN1 (0.47)	CYP11B1CYP11B2MEN1KMT2AMAPT
	SCHEMBL15453682	0.89	CYP11B1 (0.44)	CYP11B1CYP11B2PIK3CACYP3A4CYP2C9
	SCHEMBL19171464	0.89	CYP11B1 (0.44)	CYP11B1CYP11B2PIK3CACYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.