Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 3/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10587392 | 0.70 | ADORA2B (0.44) | PARG | |
| SCHEMBL20011251 | 0.68 | TRPA1 (0.36) | PARGGRIN1GRIN2B | |
| SCHEMBL18256028 | 0.67 | ADORA2B (0.55) | GRIN1GRIN2B | |
| SCHEMBL4557788 | 0.66 | TNF (0.46) | KDM4EALDH1A1 | |
| SCHEMBL17619852 | 0.64 | TRPA1 (0.55) | PARGGRIN1GRIN2B | |
| SCHEMBL20011175 | 0.63 | PARG (0.31) | PARG | |
| SCHEMBL17619778 | 0.63 | TRPA1 (0.56) | PARGGRIN1GRIN2B | |
| SCHEMBL20129919 | 0.62 | GRIN1 (0.64) | PARGGRIN1GRIN2BHSD17B10 | |
| SCHEMBL18819089 | 0.61 | TNF (0.31) | — | |
| SCHEMBL20011542 | 0.60 | TNF (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299371-A1 | HYDROXYL PURINE COMPOUNDS AND USE THEREOF | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2018-03-28 | — | — | EP | disclosed |