Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 6/20 | 0.46 |
| ▸ | PDE4A | P27815 | 5/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28472258 | 0.75 | TNF (0.47) | TNFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20011219 | 0.73 | CHRM2 (0.35) | TNF | |
| SCHEMBL18819089 | 0.73 | TNF (0.31) | TNF | |
| SCHEMBL20011542 | 0.72 | TNF (0.35) | TNF | |
| SCHEMBL20011251 | 0.72 | TRPA1 (0.36) | TNFMAPT | |
| SCHEMBL10587392 | 0.72 | ADORA2B (0.44) | ADORA2BBLM | |
| SCHEMBL7624763 | 0.68 | PDE4A (0.41) | TNFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20011545 | 0.66 | PARG (0.41) | KDM4EALDH1A1 | |
| SCHEMBL18119896 | 0.66 | TNF (0.49) | TNFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19246134 | 0.65 | ALDH1A1 (0.32) | LMNAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563565-B1 | Method of preparing bio-identical hormones | Matsuo, Susan (US) | 2009-07-21 | — | — | US | disclosed |
| US-7354608-B1 | Bio-identical hormones and method of use | Matsuo, Susan (US) | 2008-04-08 | — | — | US | disclosed |
| US-6967194-B1 | Bio-identical hormones and method of use | Matsuo, Susan (US) | 2005-11-22 | — | — | US | disclosed |