Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 18/20 | 0.58 |
| ▸ | KDR | P35968 | 5/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.56 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.56 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20012944 | 0.92 | TNK2 (0.53) | FGFR3KCNH2 | |
| SCHEMBL20012947 | 0.86 | WEE1 (0.52) | FGFR3EGFR | |
| SCHEMBL20012945 | 0.86 | INSR (0.62) | FGFR3KDRFGFR1FGFR2FGFR4 | |
| SCHEMBL20012909 | 0.85 | PDGFRB (0.50) | FGFR3KDRFGFR1FGFR2FGFR4 | |
| SCHEMBL15243958 | 0.82 | FGFR3 (0.73) | FGFR3KDRKCNH2FGFR1FGFR2 | |
| SCHEMBL18912619 | 0.79 | FGFR3 (0.74) | FGFR3KDRKCNH2FGFR1FGFR2 | |
| SCHEMBL15244149 | 0.78 | FGFR3 (0.69) | FGFR3KDRKCNH2FGFR1FGFR2 | |
| SCHEMBL15243956 | 0.78 | FGFR3 (0.73) | FGFR3KDRKCNH2FGFR1FGFR2 | |
| SCHEMBL20012920 | 0.77 | TTK (0.57) | FGFR1EGFR | |
| SCHEMBL21280246 | 0.76 | FGFR3 (0.70) | FGFR3KDRKCNH2FGFR1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018056621-A1 | NOVEL IMIDAZOLYL PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER | 재단법인 대구경북첨단의료산업진흥재단 | 2018-03-29 | — | — | WO | disclosed |