Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 3/20 | 0.57 |
| ▸ | ALK | Q9UM73 | 7/20 | 0.54 |
| ▸ | INSR | P06213 | 5/20 | 0.54 |
| ▸ | IGF1R | P08069 | 4/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.51 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 4/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | MAPK7 | Q13164 | 2/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20012902 | 0.93 | INSR (0.60) | TTKALKINSRIGF1RLRRK2 | |
| SCHEMBL20012945 | 0.91 | INSR (0.62) | ALKINSRIGF1RLRRK2CAMK2D | |
| SCHEMBL20012906 | 0.87 | CDK4 (0.46) | IGF1RFGFR1PTK2 | |
| SCHEMBL20012909 | 0.79 | PDGFRB (0.50) | ALKINSRIGF1REGFRFGFR1 | |
| SCHEMBL30957983 | 0.78 | TTK (0.61) | TTKALKINSRIGF1RLRRK2 | |
| SCHEMBL20012991 | 0.78 | FGFR1 (0.53) | IGF1RFGFR1 | |
| SCHEMBL20516347 | 0.78 | TTK (0.61) | TTKALKINSRIGF1RLRRK2 | |
| SCHEMBL30957977 | 0.78 | TTK (0.61) | TTKALKINSRIGF1RLRRK2 | |
| SCHEMBL20012903 | 0.77 | SYK (0.53) | TTKIGF1R | |
| SCHEMBL20012932 | 0.77 | FGFR3 (0.58) | EGFRFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018056621-A1 | NOVEL IMIDAZOLYL PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER | 재단법인 대구경북첨단의료산업진흥재단 | 2018-03-29 | — | — | WO | disclosed |