Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18324786 | 0.83 | ALDH1A1 (0.42) | TP53MAPTPOLBCYP2C19ALDH1A1 | |
| SCHEMBL18324877 | 0.69 | TP53 (0.39) | TP53MAPTPOLBALDH1A1KCNH2 | |
| SCHEMBL18324872 | 0.69 | KCNH2 (0.48) | TP53MAPTSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL20340154 | 0.68 | GSK3B (0.46) | MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL18324880 | 0.68 | KDM4E (0.47) | EPHX2ALDH1A1MEN1KMT2A | |
| SCHEMBL6645803 | 0.67 | NOS3 (0.44) | TP53MAPTSMN1; SMN2POLBCYP1A2 | |
| SCHEMBL24112730 | 0.67 | PGR (0.54) | POLBCYP1A2CA1CA2EPHX2 | |
| SCHEMBL9651557 | 0.67 | PGR (0.54) | POLBCYP1A2CA1CA2EPHX2 | |
| SCHEMBL16566110 | 0.67 | IDO1 (0.46) | MAPTALDH1A1 | |
| SCHEMBL18324883 | 0.67 | ALDH1A1 (0.42) | MAPTSMN1; SMN2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9931347-B2 | Pharmaceutical compound | IOMET PHARMA LTD. (US) | 2018-04-03 | — | — | US | disclosed |
| US-9931347-B2 | Pharmaceutical compound | IOMET PHARMA LTD. (US) | 2018-04-03 | — | — | US | disclosed |