Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19400061 | 0.81 | — | — | |
| SCHEMBL9294282 | 0.80 | GAA (0.40) | ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL536285 | 0.80 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL21160100 | 0.74 | GAA (0.31) | GAA | |
| SCHEMBL18084166 | 0.73 | GAA (0.36) | ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL1149368 | 0.73 | — | — | |
| SCHEMBL10999225 | 0.71 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL14420197 | 0.70 | GAA (0.38) | ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL19275048 | 0.70 | GAA (0.48) | GAA | |
| SCHEMBL27339480 | 0.70 | GAA (0.33) | ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9931420-B2 | Methods of making DLL3 antibody drug conjugates | ABBVIE STEMCENTRX LLC (US) | 2018-04-03 | — | — | US | disclosed |