Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24018628 | 0.76 | ADAM17 (0.67) | ADAM17 | |
| SCHEMBL20621743 | 0.72 | ADAM17 (0.61) | ADAM17KMT2A | |
| SCHEMBL24018577 | 0.69 | ADAM17 (0.58) | ADAM17 | |
| SCHEMBL20621776 | 0.68 | ADAM17 (0.54) | ADAM17L3MBTL1 | |
| SCHEMBL18929127 | 0.67 | ADAM17 (0.55) | ADAM17 | |
| SCHEMBL20622024 | 0.66 | ADAM17 (0.55) | ADAM17 | |
| SCHEMBL20621779 | 0.66 | ADAM17 (0.55) | ADAM17 | |
| SCHEMBL24952371 | 0.66 | ADAM17 (0.51) | ADAM17L3MBTL1KMT2A | |
| SCHEMBL24018638 | 0.66 | ADAM17 (0.76) | ADAM17L3MBTL1 | |
| SCHEMBL24208233 | 0.66 | L3MBTL1 (0.51) | ADAM17L3MBTL1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9931414-B2 | Pyrrolobenzodiazepine-antibody conjugates | MEDIMMUNE LIMITED (GB) | 2018-04-03 | — | — | US | disclosed |