Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18925539 | 0.78 | LMNA (0.44) | — | |
| SCHEMBL24018628 | 0.76 | ADAM17 (0.67) | ADAM17 | |
| SCHEMBL20621743 | 0.72 | ADAM17 (0.61) | ADAM17 | |
| SCHEMBL42947 | 0.70 | MGLL (0.60) | — | |
| SCHEMBL22184048 | 0.68 | MGLL (0.38) | — | |
| SCHEMBL7463346 | 0.67 | CYP3A4 (0.42) | — | |
| SCHEMBL20017010 | 0.67 | ADAM17 (0.55) | ADAM17 | |
| SCHEMBL10652128 | 0.66 | ELANE (0.55) | — | |
| SCHEMBL24018577 | 0.66 | ADAM17 (0.58) | ADAM17 | |
| SCHEMBL24018638 | 0.66 | ADAM17 (0.76) | ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873281-B2 | Conjugates of cell binding molecules with cytotoxic agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2024-01-16 | — | — | US | disclosed |
| US-11767294-B2 | Conjugates of cell binding molecules with cytotoxic agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-09-26 | — | — | US | disclosed |
| WO-2021212638-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2021-10-28 | — | — | WO | disclosed |
| US-20200172480-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-06-04 | — | — | US | disclosed |
| US-20190330149-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2019-10-31 | — | — | US | disclosed |
| US-10399941-B2 | Conjugates of cell binding molecules with cytotoxic agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2019-09-03 | — | — | US | disclosed |
| US-20180021448-A9 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2018-01-25 | — | — | US | disclosed |
| US-20170296663-A1 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2017-10-19 | — | — | US | disclosed |
| US-20170157262-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330149-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | CD4, CD2, CD47 | ADAM17 3067/4885 |
| US-10399941-B2 | Conjugates of cell binding molecules with cytotoxic agents | CD4, CD2, CD47 | ADAM17 3067/4885 |
| US-20170157262-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | CD4, CD2, CD47 | ADAM17 3288/4885 |
| US-11873281-B2 | Conjugates of cell binding molecules with cytotoxic agents | CD4, CD2, CD47 | ADAM17 3633/4885 |
| US-20200172480-A1 | CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS | CD4, CD2, CD47 | ADAM17 3633/4885 |
| US-11767294-B2 | Conjugates of cell binding molecules with cytotoxic agents | CD4, CD2, CD47 | ADAM17 3067/4885 |
| US-20180021448-A9 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | CD4, CD2, CD47 | ADAM17 3067/4885 |
| US-20170296663-A1 | Conjugates of Cell Binding Molecules with Cytotoxic Agents | CD4, CD2, CD47 | ADAM17 3067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.