Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16566170 | 0.82 | ALDH1A1 (0.50) | L3MBTL1GAALMNAALDH1A1HPGD | |
| SCHEMBL24208224 | 0.77 | L3MBTL1 (0.46) | L3MBTL1KMT2AGAALMNAALDH1A1 | |
| SCHEMBL14821834 | 0.76 | ALDH1A1 (0.61) | KMT2AGAALMNAALDH1A1HPGD | |
| SCHEMBL20375597 | 0.75 | MAPT (0.42) | LMNAALDH1A1TDP1MAPTADAM17 | |
| SCHEMBL13057567 | 0.74 | ALDH1A1 (0.51) | L3MBTL1KMT2AGAAALDH1A1HPGD | |
| SCHEMBL12235539 | 0.74 | HSP90AA1 (0.59) | L3MBTL1KMT2AGAALMNAALDH1A1 | |
| SCHEMBL13478303 | 0.74 | L3MBTL1 (0.47) | L3MBTL1GAALMNAALDH1A1HPGD | |
| SCHEMBL8312797 | 0.74 | ALDH1A1 (0.56) | KMT2AGAAALDH1A1HPGDKDM4E | |
| SCHEMBL16450893 | 0.74 | HSP90AA1 (0.59) | L3MBTL1KMT2AGAALMNAALDH1A1 | |
| SCHEMBL3485977 | 0.74 | ALDH1A1 (0.58) | GAALMNAALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220016261-A1 | PYRROLOBENZODIAZEPINE-ANTIBODY CONJUGATES | OWL ROCK OPPORTUNISTIC MASTER FUND I, L.P. | 2022-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220016261-A1 | PYRROLOBENZODIAZEPINE-ANTIBODY CONJUGATES | PDCD10, CD79B, SBDS | L3MBTL1 142/4885KMT2A 1216/4885GAA 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.