Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 4/20 | 0.40 |
| ▸ | NOS3 | P29474 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | ILK | Q13418 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23785507 | 0.84 | ALDH1A1 (0.39) | ALDH1A1TSHRHTR7NPC1PKM | |
| SCHEMBL2767319 | 0.81 | NR1H4 (0.43) | ALDH1A1TSHRPDCD1CD274CYP2C19 | |
| SCHEMBL2704056 | 0.79 | ALDH1A1 (0.45) | ALDH1A1TSHRNPC1PKMRAB9A | |
| SCHEMBL13177068 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRNPC1PKMRAB9A | |
| SCHEMBL30216932 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRNPC1PKMRAB9A | |
| SCHEMBL21151467 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRNOS1NOS3NPC1 | |
| SCHEMBL23202425 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRNPC1PKMRAB9A | |
| SCHEMBL28987609 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRNPC1PKMRAB9A | |
| SCHEMBL1253514 | 0.76 | HTR7 (0.50) | NOS1NOS3HTR7NPC1RAB9A | |
| SCHEMBL31056330 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TSHRNPC1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3381917-B1 | IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF | BELLUS HEALTH COUGH INC (CA) | 2021-09-08 | — | — | EP | disclosed |
| EP-2951177-B1 | IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF | NEOMED INST (CA) | 2018-04-04 | — | — | EP | disclosed |