Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 6/20 | 0.60 |
| ▸ | CCNB2 | O95067 | 5/20 | 0.60 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.60 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.60 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2006199 | 0.81 | TMIGD3 (0.60) | CDK1CCNB2CCNB1CCNB3TMIGD3 | |
| SCHEMBL15167431 | 0.77 | HTT (0.67) | CDK1CCNB2CCNB1CCNB3TMIGD3 | |
| SCHEMBL28068467 | 0.76 | TMIGD3 (0.77) | CDK1CCNB2CCNB1CCNB3TMIGD3 | |
| SCHEMBL17933852 | 0.74 | ADORA2A (0.74) | CDK1CCNB2CCNB1CCNB3TMIGD3 | |
| SCHEMBL91115 | 0.73 | CDK1 (0.55) | CDK1CCNB2CCNB1CCNB3TMIGD3 | |
| SCHEMBL27734468 | 0.73 | TMIGD3 (1.00) | CDK1CCNB2CCNB1CCNB3TMIGD3 | |
| SCHEMBL458946 | 0.73 | TMIGD3 (0.77) | CDK1CCNB2CCNB1CCNB3TMIGD3 | |
| SCHEMBL21348733 | 0.71 | TMIGD3 (0.58) | CDK1CCNB2CCNB1CCNB3TMIGD3 | |
| SCHEMBL22571186 | 0.70 | TMIGD3 (0.81) | CDK1CCNB2CCNB1CCNB3TMIGD3 | |
| SCHEMBL27967736 | 0.70 | RAB9A (0.70) | CDK1CCNB2CCNB1CCNB3TMIGD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245031-B1 | 6,9-DISUBSTITUTED PURINE DERIVATIVES AND THEIR USE AS COSMETICS AND COSMETIC COMPOSITIONS | INST OF EX BOTANY ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2014-02-26 | — | — | EP | disclosed |
| US-8575182-B2 | 6, 9-disubstituted purine derivatives and their use as cosmetics and cosmetic compositions | Institute of Experimental Botany, Academy of Sciences of the Czeck Republic (CZ) | 2013-11-05 | — | — | US | disclosed |
| US-20110230503-A1 | 6, 9-Disubstituted Purine Derivatives and Their Use as Cosmetics and Cosmetic Compositions | SZUCOVA LUCIE | 2011-09-22 | — | — | US | disclosed |
| US-7960397-B2 | 6,9-disubstituted purine derivatives and their use as cosmetics and cosmetic compositions | INSTITUTE OF EXPERIMENTAL BOTANY, ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2011-06-14 | — | — | US | disclosed |
| US-20090170879-A1 | 6,9-Disubstituted Purine Derivatives and Their Use as Cosmetics and Cosmetic Compositions | SZUCOVA LUCIE | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170879-A1 | 6,9-Disubstituted Purine Derivatives and Their Use as Cosmetics and Cosmetic Compositions | P2RY6, UMPS, PNP | CDK1 1801/4885CCNB2 2912/4885CCNB1 2876/4885 |
| US-20110230503-A1 | 6, 9-Disubstituted Purine Derivatives and Their Use as Cosmetics and Cosmetic Compositions | P2RY6, UMPS, PNP | CDK1 1801/4885CCNB2 2912/4885CCNB1 2876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.