Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16744504 | 0.83 | ALDH1A1 (0.57) | MAPTTP53ALDH1A1HTTGAA | |
| SCHEMBL23348993 | 0.83 | TRPC3 (0.50) | MAPTTP53ALDH1A1POLBHTT | |
| SCHEMBL26618064 | 0.83 | ALDH1A1 (0.43) | MAPTTP53THRBALDH1A1POLB | |
| SCHEMBL17871698 | 0.82 | ALDH1A1 (0.56) | MAPTTP53ALDH1A1MEN1KMT2A | |
| SCHEMBL25487206 | 0.82 | SMN1; SMN2 (0.49) | ALDH1A1GAASMN1; SMN2FFAR4 | |
| SCHEMBL19386343 | 0.81 | PIM1 (0.45) | MAPTALDH1A1SMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL20424771 | 0.81 | ALDH1A1 (0.48) | MAPTTP53ALDH1A1POLBHTT | |
| SCHEMBL5160655 | 0.80 | MEN1 (0.59) | THRBALDH1A1POLBHTTGAA | |
| SCHEMBL19601711 | 0.79 | ALDH1A1 (0.41) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL28621356 | 0.79 | HTR1A (0.51) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3031799-B1 | AROMATIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2018-04-04 | — | — | EP | disclosed |