Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20019966 | 0.81 | NPC1 (0.37) | SIGMAR1 | |
| SCHEMBL20019870 | 0.77 | PTGS1 (0.38) | — | |
| SCHEMBL20019907 | 0.75 | SIGMAR1 (0.32) | SIGMAR1 | |
| SCHEMBL9231800 | 0.71 | MAPT (0.42) | — | |
| SCHEMBL25065902 | 0.71 | ALDH1A1 (0.36) | — | |
| SCHEMBL20019770 | 0.71 | PNMT (0.33) | — | |
| Acetic Acid SCHEMBL7106412 | 0.69 | CYP4F2 (0.35) | — | |
| SCHEMBL28713998 | 0.68 | GPR35 (0.32) | — | |
| SCHEMBL31226359 | 0.67 | TSHR (0.42) | — | |
| SCHEMBL2927011 | 0.66 | HSD17B10 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697229-B1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MELINTA THERAPEUTICS INC (US) | 2018-04-04 | — | — | EP | disclosed |