Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12549142 | 0.88 | TYK2 (0.32) | LMNAELANETYK2 | |
| SCHEMBL12070469 | 0.88 | TYK2 (0.32) | ELANETYK2 | |
| SCHEMBL15483435 | 0.86 | LMNA (0.36) | LMNAELANETYK2 | |
| SCHEMBL883446 | 0.86 | MAPT (0.38) | LMNATYK2 | |
| SCHEMBL8008964 | 0.79 | NPC1 (0.37) | LMNATYK2 | |
| SCHEMBL8006213 | 0.78 | ADORA2A (0.40) | — | |
| SCHEMBL7944203 | 0.77 | CTSS (0.40) | LMNA | |
| SCHEMBL8005282 | 0.75 | CYP1B1 (0.37) | — | |
| SCHEMBL13336763 | 0.75 | CTSS (0.37) | LMNATYK2 | |
| SCHEMBL12362342 | 0.74 | KDM4E (0.41) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180093943-A1 | Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV | Janssen Pharmaceuticals, Inc. (US) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093943-A1 | Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV | CTRC, HAVCR2, HGFAC | LMNA 1062/4885ELANE 2461/4885TYK2 3782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.