Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL883446 | 0.88 | MAPT (0.38) | NPC1RAB9AMAPTKDM4ELMNA | |
| SCHEMBL314499 | 0.88 | MAPT (0.35) | NPC1RAB9AMAPTKDM4ELMNA | |
| SCHEMBL8003749 | 0.88 | NPC1 (0.37) | NPC1RAB9AMAPTKDM4ELMNA | |
| SCHEMBL8006684 | 0.82 | NPC1 (0.37) | NPC1RAB9AMAPTKDM4ELMNA | |
| SCHEMBL8003707 | 0.81 | RAB9A (0.36) | NPC1RAB9AMAPTKDM4ELMNA | |
| SCHEMBL8002647 | 0.81 | APLNR (0.35) | MAPTKDM4ETYK2APLNRALDH1A1 | |
| SCHEMBL7944203 | 0.80 | CTSS (0.40) | NPC1RAB9AMAPTKDM4ELMNA | |
| SCHEMBL20021635 | 0.79 | LMNA (0.34) | LMNATYK2 | |
| SCHEMBL15483435 | 0.79 | LMNA (0.36) | NPC1RAB9AMAPTKDM4ELMNA | |
| SCHEMBL13336763 | 0.78 | CTSS (0.37) | NPC1RAB9AMAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009099596-A2 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARAMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |