SCHEMBL20022104

SCHEMBL20022104

Cc1cccc(-c2cccc(-c3cccc(-c4cccc(C(F)(F)F)c4)c3)c2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN5 P54829 2/20 0.60
AR P10275 1/20 0.50
IKBKB O14920 1/20 0.47
KDM4E B2RXH2 1/20 0.47
HSD17B10 Q99714 1/20 0.47
BRD4 O60885 1/20 0.47
MAOB P27338 1/20 0.47
NFE2L2 Q16236 1/20 0.47
MEN1 O00255 1/20 0.46
HTT P42858 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
KDM1A O60341 1/20 0.46
KCNK3 O14649 1/20 0.45
KCNK9 Q9NPC2 1/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
KIF11 P52732 1/20 0.45
RAPGEF4 Q8WZA2 1/20 0.45
IDO1 P14902 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20022132 1.00 PTPN5 (0.60) PTPN5ARIKBKBKDM4EHSD17B10
SCHEMBL20022097 0.98 PTPN5 (0.58) PTPN5ARIKBKBKDM4EHSD17B10
SCHEMBL2662898 0.98 PTPN5 (0.62) PTPN5ARIKBKBKDM4EHSD17B10
SCHEMBL8260296 0.88 PTPN5 (0.56) PTPN5ARIKBKBKDM4EHSD17B10
SCHEMBL26375414 0.86 PTPN5 (0.50) PTPN5IKBKBKDM4EHSD17B10BRD4
SCHEMBL20022126 0.86 KIF11 (0.57) PTPN5ARMAOBKIF11
SCHEMBL20022093 0.86 KIF11 (0.57) PTPN5ARMAOBKIF11
SCHEMBL148048 0.85 NFE2L2 (0.55) PTPN5NFE2L2MEN1HTTRAB9A
SCHEMBL29678302 0.85 TSHR (0.58) MAOBKDM1ATSHRMAPK1KIF11
SCHEMBL1263144 0.85 TSHR (0.58) MAOBKDM1ATSHRMAPK1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136341-B2 Polycyclic aromatic compound and light emission layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2021-10-05 US disclosed
US-10689402-B2 Polycyclic aromatic compound and light emission layer-forming composition JNC CORPORATION (JP) 2020-06-23 US disclosed
US-20200190116-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2020-06-18 US disclosed
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-04-05 US disclosed
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200190116-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION TYR, NOD2, AHR PTPN5 1498/4885AR 1475/4885IKBKB 2780/4885
US-11136341-B2 Polycyclic aromatic compound and light emission layer-forming composition TYR, NOD2, AHR PTPN5 1498/4885AR 1475/4885IKBKB 2780/4885
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION TYR, NOD2, AHR PTPN5 1498/4885AR 1475/4885IKBKB 2780/4885
US-10689402-B2 Polycyclic aromatic compound and light emission layer-forming composition TYR, NOD2, AHR PTPN5 1498/4885AR 1475/4885IKBKB 2780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.