SCHEMBL20022112

SCHEMBL20022112

Cc1cccc(-c2cc(-c3ccc(C(F)(F)F)cc3)cc(-c3ccc(C(F)(F)F)cc3)c2)c1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 7/20 0.55
AR P10275 1/20 0.51
DHODH Q02127 1/20 0.50
PTPN5 P54829 2/20 0.49
AGXT P21549 1/20 0.49
PAX8 Q06710 1/20 0.46
PDK2 Q15119 1/20 0.44
ENPP3 O14638 1/20 0.42
GLO1 Q04760 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20022126 0.98 KIF11 (0.57) KIF11ARDHODHPTPN5AGXT
SCHEMBL20022093 0.98 KIF11 (0.57) KIF11ARDHODHPTPN5AGXT
SCHEMBL5547675 0.96 KIF11 (0.59) KIF11ARDHODHPTPN5AGXT
SCHEMBL26824942 0.89 PTPN5 (0.53) KIF11ARPTPN5AGXTPDK2
SCHEMBL26831184 0.89 KIF11 (0.59) KIF11ARDHODHPTPN5AGXT
SCHEMBL20022097 0.87 PTPN5 (0.58) KIF11ARPTPN5
SCHEMBL19301032 0.86 KIF11 (0.54) KIF11
SCHEMBL26821713 0.86 KIF11 (0.73) KIF11DHODHAGXTGLO1
SCHEMBL20022104 0.85 PTPN5 (0.60) KIF11ARPTPN5
SCHEMBL20022132 0.85 PTPN5 (0.60) KIF11ARPTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136341-B2 Polycyclic aromatic compound and light emission layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2021-10-05 US disclosed
US-10689402-B2 Polycyclic aromatic compound and light emission layer-forming composition JNC CORPORATION (JP) 2020-06-23 US disclosed
US-20200190116-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2020-06-18 US disclosed
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-04-05 US disclosed
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2018-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200190116-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION TYR, NOD2, AHR KIF11 2192/4885AR 1475/4885DHODH 3800/4885
US-11136341-B2 Polycyclic aromatic compound and light emission layer-forming composition TYR, NOD2, AHR KIF11 2192/4885AR 1475/4885DHODH 3800/4885
US-20180094000-A1 POLYCYCLIC AROMATIC COMPOUND AND LIGHT EMISSION LAYER-FORMING COMPOSITION TYR, NOD2, AHR KIF11 2192/4885AR 1475/4885DHODH 3800/4885
US-10689402-B2 Polycyclic aromatic compound and light emission layer-forming composition TYR, NOD2, AHR KIF11 2192/4885AR 1475/4885DHODH 3800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.