Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | EZH2 | Q15910 | 4/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18309857 | 0.86 | KCNH2 (0.64) | KCNH2HTR2AHTR2CCYP1A2CYP3A4 | |
| SCHEMBL20022665 | 0.84 | HTR2A (0.56) | KCNH2HTR2AHTR2CCYP1A2CYP3A4 | |
| SCHEMBL980 | 0.80 | KCNH2 (0.76) | KCNH2HTR2AHTR2CCYP1A2CYP3A4 | |
| Fumaric Acid SCHEMBL1534 | 0.74 | KCNH2 (0.67) | KCNH2HTR2AHTR2CCYP1A2CYP3A4 | |
| Maleic Acid SCHEMBL1533 | 0.74 | KCNH2 (0.67) | KCNH2HTR2AHTR2CCYP1A2CYP3A4 | |
| SCHEMBL16201649 | 0.73 | CSNK2A2 (0.40) | KCNH2HTR2AHTR2CCYP1A2CYP3A4 | |
| Alosetron SCHEMBL148316 | 0.69 | HTR2A (0.74) | KCNH2HTR2AHTR2CCYP1A2CYP3A4 | |
| Alosetron SCHEMBL7371660 | 0.69 | CASP6 (0.74) | KCNH2HTR2AHTR2CCYP1A2CYP3A4 | |
| Alosetron SCHEMBL311317 | 0.69 | CASP6 (0.74) | KCNH2HTR2AHTR2CCYP1A2CYP3A4 | |
| SCHEMBL20027463 | 0.68 | KCNH2 (0.57) | KCNH2HTR2AHTR2CCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180094015-A1 | ENZYME-DIRECTED IMMUNOSTIMULANT AND USES THEREOF CROSS-REFERENCE TO RELATED APPLICATION(S) | WASHINGTON STATE UNIVERSITY | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180094015-A1 | ENZYME-DIRECTED IMMUNOSTIMULANT AND USES THEREOF CROSS-REFERENCE TO RELATED APPLICATION(S) | ACHE, GUSB, ENGASE | KCNH2 4788/4885HTR2A 4185/4885HTR2C 4443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.