Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 2/20 | 0.57 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.57 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.57 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7060700 | 0.91 | TDP1 (0.56) | PLAAT5PLAAT4TDP1L3MBTL1LMNA | |
| SCHEMBL21235487 | 0.85 | ALDH1A1 (0.60) | TDP1L3MBTL1LMNAKMT2AMAPT | |
| SCHEMBL7059127 | 0.85 | PLAAT3 (0.61) | PLAAT3PLAAT5PLAAT2PLAAT4TDP1 | |
| SCHEMBL7061713 | 0.85 | PLAAT3 (0.57) | PLAAT3PLAAT5PLAAT2PLAAT4TDP1 | |
| SCHEMBL7061979 | 0.85 | PLAAT3 (0.57) | PLAAT3PLAAT5PLAAT2PLAAT4TDP1 | |
| SCHEMBL7640279 | 0.84 | ALDH1A1 (0.54) | TDP1L3MBTL1LMNAKMT2AMAPT | |
| SCHEMBL9726057 | 0.82 | CYP4F2 (0.53) | PLAAT3PLAAT5PLAAT2PLAAT4TDP1 | |
| SCHEMBL304796 | 0.82 | L3MBTL1 (0.55) | PLAAT3PLAAT5PLAAT2PLAAT4TDP1 | |
| SCHEMBL7058748 | 0.82 | PTGER1 (0.46) | LMNAMEN1GAAKMT2AMAPT | |
| SCHEMBL20022993 | 0.81 | L3MBTL1 (0.56) | L3MBTL1LMNAMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180093981-A1 | 2-Acylaminopropoanol-Type Glucosylceramide Synthase Inhibitors | GENZYME CORPORATION | 2018-04-05 | — | — | US | disclosed |
| US-20180093981-A1 | 2-Acylaminopropoanol-Type Glucosylceramide Synthase Inhibitors | GENZYME CORPORATION | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093981-A1 | 2-Acylaminopropoanol-Type Glucosylceramide Synthase Inhibitors | ASAH2, GBA1, GAA | PLAAT3 938/4885PLAAT5 1023/4885PLAAT2 191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.