Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.49 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.49 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28404120 | 0.97 | L3MBTL1 (0.52) | L3MBTL1TDP1SMN1; SMN2ALDH1A1KEAP1 | |
| SCHEMBL1858472 | 0.90 | ALOX5 (0.56) | L3MBTL1TDP1SMN1; SMN2PLAAT5PLAAT4 | |
| SCHEMBL304577 | 0.89 | L3MBTL1 (0.55) | L3MBTL1TDP1SMN1; SMN2ALDH1A1KEAP1 | |
| SCHEMBL304579 | 0.89 | L3MBTL1 (0.55) | L3MBTL1TDP1SMN1; SMN2ALDH1A1KEAP1 | |
| SCHEMBL7635946 | 0.88 | ALOX5 (0.55) | L3MBTL1SMN1; SMN2PLAAT5PLAAT4MAPT | |
| SCHEMBL7330817 | 0.88 | FFAR1 (0.62) | PLAAT5PLAAT4PLAAT3PLAAT2FFAR1 | |
| SCHEMBL9725829 | 0.87 | FFAR1 (0.65) | L3MBTL1TDP1ALDH1A1FFAR1ALOX5 | |
| SCHEMBL1107673 | 0.87 | SMN1; SMN2 (0.52) | L3MBTL1TDP1SMN1; SMN2ALDH1A1KEAP1 | |
| SCHEMBL8816730 | 0.87 | MAPT (0.57) | SMN1; SMN2PLAAT5PLAAT4MAPTPLAAT3 | |
| SCHEMBL7640337 | 0.87 | MAPT (0.57) | SMN1; SMN2PLAAT5PLAAT4MAPTPLAAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 625 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119913221-A | Method for synthesizing ethyl 2-N-benzylamino-4-phenylbutyrate by using enzymatic method | 中国科学院天津工业生物技术研究所 | 2025-05-02 | — | — | CN | claimed |
| CN-117866221-A | Super-stable hydrogen bond organic framework material for regenerating light-driven cofactor NADH, and synthesis method and application thereof | 南京师范大学 | 2024-04-12 | — | — | CN | claimed |
| CN-115851641-A | Fusion enzyme for efficiently producing (R) -2-hydroxy-4-phenylbutyric ethyl butyrate and application thereof | 浙江工业大学 | 2023-03-28 | — | — | CN | claimed |
| CN-115820622-A | Double-enzyme self-assembly compound and application of compound in synthesizing (R) -2-hydroxy-4-phenylbutyrate | 浙江工业大学 | 2023-03-21 | — | — | CN | claimed |
| CN-109929885-B | Method for preparing ethyl gamma-2-hydroxy-4-phenylbutyrate by coupling extraction of enzyme membrane reactor | 江苏惠利生物科技有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-114574455-A | Method for forming supramolecular hydrogel for biocatalysis by utilizing enzyme self-assembly | 清华大学 | 2022-06-03 | — | — | CN | claimed |
| CN-114249795-A | Preparation method of enalapril maleate and intermediate thereof | 佛山奕安赛医药科技有限公司 | 2022-03-29 | — | — | CN | claimed |
| CN-111218441-B | Magnetic immobilized yeast cell and application thereof in preparation of (R) -2-hydroxy-4-phenylbutyrate ethyl ester | 浙江工业大学 | 2022-03-18 | — | — | CN | claimed |
| CN-109370994-B | Carbonyl reductase mutant mut-AcCR (G152L/Y189N) and application and coding gene thereof | 华南理工大学 | 2021-05-14 | — | — | CN | claimed |
| CN-112225778-A | Preparation method of enalapril maleate | 辰欣药业股份有限公司 | 2021-01-15 | — | — | CN | claimed |
| US-20070072278-A1 | Using glucose dehydrogenase to asymmetrically reducing a 2-oxo-4-phenylbutyrate to produce a (R)-2-hydroxy-4-phenylbutyrate; industrial scale | SUMITOMO CHEMICAL COMPANY LIMITED | 2007-03-29 | — | — | US | claimed |
| EP-1762625-A1 | Reductase gene and use thereof | Sumitomo Chemical Company, Limited (JP) | 2007-03-14 | — | — | EP | claimed |
| US-20050191735-A1 | Oxidoreductase | IEP GMBH (DE) | 2005-09-01 | — | — | US | claimed |
| US-20040265978-A1 | Enzymatic method for the enantioselective reduction of keto compounds | IEP GMBH (DE) | 2004-12-30 | — | — | US | claimed |
| EP-1437401-A1 | Oxidoreductase | Juelich Enzyme Products GmbH (DE) | 2004-07-14 | — | — | EP | claimed |
| EP-1383899-A2 | ENZYMATIC METHOD FOR THE ENANTIOSELECTIVE REDUCTION OF KETO COMPOUNDS | Jülich Enzyme Products GmbH (DE) | 2004-01-28 | — | — | EP | claimed |
| WO-2002086126-A2 | ENZYMATIC METHOD FOR THE ENANTIOSELECTIVE REDUCTION OF KETO COMPOUNDS | JUELICH ENZYME PRODUCTS GMBH (DE) | 2002-10-31 | — | — | WO | claimed |
| US-5066801-A | PREPARATION OF SULFONIC ACID ESTERS | CIBA-GEIGY CORPORATION (US) | 1991-11-19 | — | — | US | claimed |
| EP-0206993-B1 | SULPHONIC-ACID ESTERS | CIBA-GEIGY AG (CH) | 1990-05-23 | — | — | EP | claimed |
| US-4785089-A | Novel sulfonic acid esters and their preparation | CIBA-GEIGY CORPORATION (US) | 1988-11-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072278-A1 | Using glucose dehydrogenase to asymmetrically reducing a 2-oxo-4-phenylbutyrate to produce a (R)-2-hydroxy-4-phenylbutyrate; industrial scale | HADHB, HPD, PDHB | L3MBTL1 157/4885TDP1 688/4885SMN1; SMN2 3142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.