Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 7/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | BRD2 | P25440 | 2/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20024193 | 0.86 | KDM4E (0.33) | KDM4EATML3MBTL1NPY5RTSPO | |
| SCHEMBL20030006 | 0.85 | ALOX5 (0.39) | KDM4EATML3MBTL1NPY5RPRKDC | |
| SCHEMBL17885352 | 0.84 | KDM4E (0.44) | KDM4EATML3MBTL1TSPOPRKDC | |
| SCHEMBL22007492 | 0.84 | KDM4E (0.36) | KDM4EATML3MBTL1NPY5RTSPO | |
| SCHEMBL16441451 | 0.83 | KDM4E (0.38) | KDM4EATML3MBTL1TSPOPRKDC | |
| SCHEMBL20024233 | 0.82 | L3MBTL1 (0.40) | KDM4EATML3MBTL1NPY5RTSPO | |
| SCHEMBL15988940 | 0.82 | KDM4E (0.47) | KDM4EATML3MBTL1TSPOPRKDC | |
| SCHEMBL10165773 | 0.82 | KDM4E (0.47) | KDM4EATML3MBTL1TSPOPRKDC | |
| SCHEMBL16441597 | 0.82 | KDM4E (0.37) | KDM4EATML3MBTL1TSPOPRKDC | |
| SCHEMBL18471391 | 0.82 | KDM4E (0.36) | KDM4EATML3MBTL1NPY5RPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018060218-A1 | CARBAZOLES WITH DIAZADIBENZOFURANE OR DIAZADIBENZOTHIOPHENE STRUCTURES | MERCK PATENT GMBH (DE) | 2018-04-05 | — | — | WO | disclosed |