Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 4/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20025550 | 0.90 | SIGMAR1 (0.36) | DRD2DRD3DRD4SIGMAR1KCNA3 | |
| SCHEMBL20025506 | 0.89 | DRD2 (0.39) | DRD2DRD3DRD4SIGMAR1KCNA3 | |
| SCHEMBL20001502 | 0.86 | MMP2 (0.40) | — | |
| SCHEMBL23734886 | 0.84 | MAPK1 (0.38) | DRD2DRD3DRD4SIGMAR1KCNA3 | |
| SCHEMBL20001474 | 0.84 | MMP2 (0.36) | DRD2DRD3SIGMAR1 | |
| SCHEMBL19989574 | 0.81 | MMP2 (0.37) | DRD2SIGMAR1KCNA3 | |
| SCHEMBL19989579 | 0.81 | MMP2 (0.38) | — | |
| SCHEMBL20001507 | 0.80 | MMP2 (0.41) | — | |
| SCHEMBL23735089 | 0.80 | SIGMAR1 (0.36) | DRD2DRD3DRD4SIGMAR1 | |
| SCHEMBL20025403 | 0.79 | KCNA3 (0.37) | DRD2DRD3DRD4SIGMAR1KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018062924-A1 | TETRAHYDROPYRIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | DONG-A ST CO., LTD. (KR) | 2018-04-05 | — | — | WO | disclosed |