Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23735108 | 0.87 | SIGMAR1 (0.36) | SIGMAR1DRD2HTR1DKDM4E | |
| SCHEMBL23735046 | 0.81 | SIGMAR1 (0.41) | SIGMAR1DRD2HTR1DKDM4E | |
| SCHEMBL20025547 | 0.80 | DRD2 (0.38) | SIGMAR1DRD2DRD3DRD4 | |
| SCHEMBL20001507 | 0.79 | MMP2 (0.41) | MMP2MMP3 | |
| SCHEMBL23735061 | 0.79 | DRD2 (0.43) | SIGMAR1DRD2DRD3DRD4KDM4E | |
| SCHEMBL20025550 | 0.78 | SIGMAR1 (0.36) | SIGMAR1DRD2DRD3DRD4KDM4E | |
| SCHEMBL20025506 | 0.77 | DRD2 (0.39) | SIGMAR1DRD2DRD3DRD4 | |
| SCHEMBL23734912 | 0.75 | SIGMAR1 (0.41) | SIGMAR1DRD2DRD3HTR1DKDM4E | |
| SCHEMBL23734895 | 0.75 | KCNA3 (0.37) | SIGMAR1DRD2DRD3DRD4KDM4E | |
| SCHEMBL20025454 | 0.75 | SIGMAR1 (0.37) | SIGMAR1DRD2HTR1DKDM4EMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3519387-B1 | TETRAHYDROPYRIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | DONG A ST CO LTD (KR) | 2021-08-11 | — | — | EP | disclosed |