SCHEMBL20026322

SCHEMBL20026322

CO[C@H](c1ccc(-c2ccc(C)nc2)cc1)C(CF)N=[N+]=[N-]

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13527562 1.00 MAOB (0.32) MAOB
SCHEMBL14082446 0.87 AKR1C3 (0.34) —
SCHEMBL13527622 0.87 — —
SCHEMBL14023294 0.87 — —
SCHEMBL20026167 0.87 — —
SCHEMBL13527577 0.87 MKNK1 (0.38) —
SCHEMBL14022480 0.87 LTA4H (0.34) —
SCHEMBL14022482 0.86 FTO (0.35) —
SCHEMBL13527570 0.86 LMNA (0.31) —
SCHEMBL13527559 0.85 PIK3CA (0.33) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180094016-A1 Triazole Compounds And Methods Of Making And Using The Same BioVersys AG (CH) 2018-04-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180094016-A1 Triazole Compounds And Methods Of Making And Using The Same IL33, PROKR1, VIP MAOB 1760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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