Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 4/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | CCR1 | P32246 | 6/20 | 0.39 |
| ▸ | DCAF1 | Q9Y4B6 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22885966 | 0.87 | CTSV (0.48) | PYGLCNR1CNR2CCR1DCAF1 | |
| SCHEMBL22886468 | 0.86 | PYGL (0.44) | PYGLCNR1CNR2CCR1DCAF1 | |
| SCHEMBL20028624 | 0.82 | CAPN1 (0.56) | CAPN1CTSS | |
| SCHEMBL30133607 | 0.82 | CAPN1 (0.56) | CAPN1CTSS | |
| SCHEMBL20028606 | 0.81 | PYGL (0.43) | PYGLCNR1CNR2CCR1DCAF1 | |
| SCHEMBL20027914 | 0.81 | DCAF1 (0.48) | PYGLDCAF1CAPN1 | |
| SCHEMBL20028168 | 0.81 | PYGL (0.44) | PYGLCNR1CNR2CCR1 | |
| SCHEMBL20027892 | 0.81 | PYGL (0.44) | PYGLCNR1CNR2CCR1 | |
| SCHEMBL22897214 | 0.79 | DCAF1 (0.51) | PYGLCNR1CNR2DCAF1CTSV | |
| SCHEMBL20027617 | 0.79 | PYGL (0.43) | PYGLCNR1CNR2CCR1DCAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018064119-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPEUTICS, INC. (US) | 2018-04-05 | — | — | WO | disclosed |