Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | ECE1 | P42892 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 7/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21854369 | 0.86 | CAPN1 (0.47) | ROCK2CAPN1 | |
| SCHEMBL22886609 | 0.80 | PYGL (0.45) | PYGLCCR1 | |
| SCHEMBL22886782 | 0.79 | PYGL (0.38) | PYGLROCK2CAPN1CCR1CHEK1 | |
| SCHEMBL22886421 | 0.77 | PYGL (0.38) | PYGLTHRBRAB9ACCR1ALDH1A1 | |
| SCHEMBL22886430 | 0.77 | PYGL (0.41) | PYGLTHRBRAB9ACCR1 | |
| SCHEMBL20028423 | 0.76 | CDC7 (0.42) | PYGLROCK2CCR1 | |
| SCHEMBL22886595 | 0.76 | PYGL (0.39) | PYGLRAB9APOLB | |
| SCHEMBL20028429 | 0.75 | PYGL (0.42) | PYGLMMECAPN1CCR1 | |
| SCHEMBL20028427 | 0.74 | PYGL (0.41) | PYGLCCR1 | |
| SCHEMBL20028424 | 0.73 | PYGL (0.40) | PYGLCAPN1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018064119-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPEUTICS, INC. (US) | 2018-04-05 | — | — | WO | disclosed |