Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.53 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.53 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.53 |
| ▸ | PRKACA | P17612 | 2/20 | 0.53 |
| ▸ | GSK3B | P49841 | 2/20 | 0.53 |
| ▸ | PRKX | P51817 | 2/20 | 0.53 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.53 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.53 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.47 |
| ▸ | CTSA | P10619 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.44 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.44 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29961323 | 0.84 | CTSL (0.44) | KMT2APOLBDCAF1MEN1 | |
| SCHEMBL21854166 | 0.84 | CAPN1 (0.50) | KMT2APOLBMEN1 | |
| SCHEMBL21410955 | 0.84 | CTSL (0.44) | KMT2APOLBDCAF1MEN1 | |
| SCHEMBL21854245 | 0.82 | CAPN1 (0.51) | DCAF1 | |
| SCHEMBL20028606 | 0.82 | PYGL (0.43) | ROCK2ROCK1MAPK1RPS6KA5RPS6KA4 | |
| SCHEMBL20027555 | 0.82 | CAPN1 (0.51) | DCAF1 | |
| SCHEMBL22885972 | 0.82 | CTSL (0.42) | CTSANPC1RAB9APOLBDCAF1 | |
| SCHEMBL22885979 | 0.81 | PYGL (0.46) | ROCK2ROCK1CTSACYP3A4KMT2A | |
| SCHEMBL21854134 | 0.76 | LMNA (0.44) | KMT2ANPC1RAB9APOLBMEN1 | |
| SCHEMBL20027556 | 0.76 | CAPN1 (0.48) | DCAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018064119-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | BLADE THERAPEUTICS, INC. (US) | 2018-04-05 | — | — | WO | disclosed |