SCHEMBL2002972

SCHEMBL2002972

Cc1ccc(O)c2cccnc12

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 5/20 0.72
SLC6A2 P23975 1/20 0.72
KMT2A Q03164 7/20 0.53
MEN1 O00255 6/20 0.53
MAPT P10636 6/20 0.53
LMNA P02545 5/20 0.53
SMN1; SMN2 Q16637 4/20 0.53
L3MBTL1 Q9Y468 5/20 0.52
HSP90AA1 P07900 3/20 0.52
NPC1 O15118 3/20 0.52
KDM4E B2RXH2 5/20 0.52
IDO1 P14902 2/20 0.52
MPI P34949 1/20 0.52
BRD4 O60885 1/20 0.52
METAP2 P50579 1/20 0.52
METAP1 P53582 1/20 0.52
PSMD14 O00487 1/20 0.52
COPS5 Q92905 1/20 0.52
HSP90AB1 P08238 1/20 0.52
PSMB5 P28074 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5540649 0.84 HTR1A (0.56) HTTSLC6A2KMT2AMEN1MAPT
Tiliquinol SCHEMBL30831638 0.84 HTT (1.00) HTTSLC6A2KMT2AMEN1MAPT
Tiliquinol SCHEMBL145245 0.84 HTT (1.00) HTTSLC6A2KMT2AMEN1MAPT
SCHEMBL812451 0.83 HTT (0.70) HTTSLC6A2KMT2AMEN1MAPT
SCHEMBL1920452 0.83 KDM4E (0.70) HTTSLC6A2KMT2AMEN1MAPT
Tiliquinol SCHEMBL2876839 0.82 HTT (0.96) HTTSLC6A2KMT2AMEN1MAPT
Tiliquinol SCHEMBL28651750 0.82 HTT (0.96) HTTSLC6A2KMT2AMEN1MAPT
Tiliquinol SCHEMBL4776013 0.82 HTT (0.96) HTTSLC6A2KMT2AMEN1MAPT
Tiliquinol SCHEMBL175614 0.82 HTT (0.96) HTTSLC6A2KMT2AMEN1MAPT
Tiliquinol SCHEMBL27600011 0.82 HTT (0.96) HTTSLC6A2KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250236792-A1 ETCHANT COMPOSITION FOR ETCHING SILICON AND METHOD OF FORMING PATTERN USING THE SAME DONGWOO FINE-CHEM CO., LTD. (KR) 2025-07-24 US disclosed
CN-117986220-A Method for preparing substituted chromanone derivative 杭州杜易科技有限公司 2024-05-07 CN disclosed
CN-114222734-B Method for preparing substituted chromanone derivative 杭州杜易科技有限公司 2023-12-08 CN disclosed
CN-114222734-A Method for preparing substituted chromanone derivative 杭州杜易科技有限公司 2022-03-22 CN disclosed
EP-2570418-A2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-03-20 EP disclosed
EP-1555267-B1 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES OTSUKA PHARMA CO LTD (JP) 2013-01-16 EP disclosed
US-7960155-B1 Cytochrome p450 monooxygenases and their use for oxidizing organic compounds BASF AKTIENGESELLSCHAFT (DE) 2011-06-14 US disclosed
EP-1196605-B1 NOVEL CYTOCHROME P450 MONOOXYGENASES AND THEIR USE FOR OXIDIZING ORGANIC COMPOUNDS BASF SE (DE) 2008-09-24 EP disclosed
US-7262212-B2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-08-28 US disclosed
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-05-04 US disclosed
EP-1555267-A1 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-07-20 EP disclosed
EP-1196605-A1 NOVEL CYTOCHROME P450 MONOOXYGENASES AND THEIR USE FOR OXIDIZING ORGANIC COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2002-04-17 EP disclosed
WO-2001007630-A1 NOVEL CYTOCHROME P450 MONOOXYGENASES AND THEIR USE FOR OXIDIZING ORGANIC COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2001-02-01 WO disclosed
US-5405843-A Anticancer drug potentiators MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-04-11 US disclosed
EP-0363212-B1 Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components MITSUI TOATSU CHEMICALS (JP) 1995-01-04 EP disclosed
US-5204348-A Quinoline derivatives MITSUI TOATSU CHEMICALS INC. (JP) 1993-04-20 US disclosed
US-5112817-A Anticancer Drug Potentiators MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1992-05-12 US disclosed
EP-0363212-A2 Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-04-11 EP disclosed
EP-0132714-B1 PROCESS FOR THE PREPARATION OF QUINOLINES BASF Aktiengesellschaft (DE) 1987-01-28 EP disclosed
US-3956420-A CPOLYOLEFIN COMPOSITION FOR ELECTRICAL INSULATIONFERROCENE, 8-SUBSTITUTED QUINOLINE DAINICHI-NIPPON CABLES, LTD. (JA) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles NR2C2, NR4A3, NR4A2 HTT 4644/4885SLC6A2 3396/4885KMT2A 4267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.