Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2007854 | 0.94 | FAAH (0.35) | MEN1KMT2AMAPTALDH1A1FAAH | |
| SCHEMBL2006939 | 0.91 | L3MBTL1 (0.37) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL2002486 | 0.91 | FAAH (0.43) | MEN1KMT2AMAPTFAAHALOX5 | |
| SCHEMBL2007961 | 0.90 | STAT3 (0.34) | MEN1KMT2AMAPTPKMGAA | |
| SCHEMBL2002817 | 0.89 | FAAH (0.40) | MEN1KMT2AMAPTPKMGAA | |
| SCHEMBL2002985 | 0.89 | MAPK14 (0.37) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL2006102 | 0.89 | KMT2A (0.43) | MEN1KMT2AMAPTPKMALDH1A1 | |
| SCHEMBL2011061 | 0.88 | ALOX5AP (0.39) | MEN1KMT2AMAPTPKMALDH1A1 | |
| SCHEMBL1997410 | 0.88 | MAPT (0.36) | MEN1KMT2AMAPTPKMGAA | |
| SCHEMBL2008249 | 0.85 | LMNA (0.34) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960544-B2 | Useful indole compounds | IRONWOOD PHARMACEUTICALS, INC. (US) | 2011-06-14 | — | — | US | disclosed |