SCHEMBL200309

SCHEMBL200309

O=C(OCC1CC2C=CC1C2)c1ccc2ccccc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
POLB P06746 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
HRH3 Q9Y5N1 2/20 0.44
DRD3 P35462 1/20 0.43
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
KDM4E B2RXH2 5/20 0.40
MAPT P10636 2/20 0.40
HTT P42858 1/20 0.40
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
NPC1 O15118 3/20 0.39
KMT2A Q03164 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL200408 0.88 HRH3 (0.48) ALDH1A1SMN1; SMN2POLBCYP1A2CYP3A4
SCHEMBL417008 0.85 POLB (0.43) ALDH1A1POLBKDM4ECES2NPC1
SCHEMBL14435505 0.84 PPM1B (0.47) ALDH1A1KDM4ECES2NPC1KMT2A
SCHEMBL4403504 0.84 PPM1B (0.47) ALDH1A1KDM4ECES2NPC1KMT2A
SCHEMBL200865 0.82 KDM4E (0.47) ALDH1A1SMN1; SMN2CYP1A2CYP2C19KDM4E
SCHEMBL203002 0.81 FFAR4 (0.44) ALDH1A1SMN1; SMN2KDM4EMAPTNPC1
SCHEMBL18719781 0.81 MAPT (0.50) ALDH1A1SMN1; SMN2CYP1A2CYP2D6CYP2C9
SCHEMBL19133375 0.81 CES2 (0.38) ALDH1A1SMN1; SMN2POLBKDM4ECES2
SCHEMBL200050 0.80 KDM4E (0.42) ALDH1A1SMN1; SMN2POLBCYP1A2CYP3A4
SCHEMBL10023890 0.79 MAPT (0.46) ALDH1A1SMN1; SMN2POLBKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3344671-B1 POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS PROMERUS LLC (US) 2019-11-06 EP disclosed
EP-3344671-B1 POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS PROMERUS LLC (US) 2019-11-06 EP disclosed
US-9944818-B2 Polycycloolefin polymer compositions as optical materials PROMERUS, LLC (US) 2018-04-17 US disclosed
US-9944818-B2 Polycycloolefin polymer compositions as optical materials PROMERUS, LLC (US) 2018-04-17 US disclosed
WO-2017040737-A1 POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2017-03-09 WO disclosed
US-20170058145-A1 POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2017-03-02 US disclosed
US-20170058145-A1 POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS PROMERUS, LLC (US) 2017-03-02 US disclosed
US-9417477-B2 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-20150146140-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 US disclosed
US-7719644-B2 Optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2010-05-18 US disclosed
US-20090033835-A1 Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2009-02-05 US disclosed
US-20080284957-A1 Optical Resin Film, Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
WO-2006082818-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2006-08-10 WO disclosed
US-7008569-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-03-07 US disclosed
US-20040057141-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-03-25 US disclosed