SCHEMBL200050

SCHEMBL200050

O=C(OCC1CC2C=CC1C2)c1c2ccccc2cc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.42
ALDH1A1 P00352 9/20 0.42
HPGD P15428 4/20 0.42
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
POLB P06746 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 5/20 0.39
GLA P06280 2/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPT P10636 2/20 0.38
MAPK1 P28482 2/20 0.38
LMNA P02545 1/20 0.38
ATM Q13315 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203303 0.88 KDM4E (0.40) KDM4EALDH1A1HPGDKMT2AMEN1
SCHEMBL203615 0.82 CDC25B (0.44) KDM4EALDH1A1HPGDKMT2AL3MBTL1
SCHEMBL200309 0.80 ALDH1A1 (0.46) KDM4EALDH1A1HPGDKMT2AMEN1
SCHEMBL4403504 0.79 PPM1B (0.47) KDM4EALDH1A1KMT2ATDP1MAPK1
SCHEMBL14435505 0.79 PPM1B (0.47) KDM4EALDH1A1KMT2ATDP1MAPK1
SCHEMBL2896185 0.78 ALDH1A1 (0.41) KDM4EALDH1A1HPGDKMT2AMEN1
SCHEMBL417008 0.77 POLB (0.43) KDM4EALDH1A1KMT2APOLBTDP1
SCHEMBL3718538 0.75 KDM4E (0.40) KDM4EALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL200865 0.74 KDM4E (0.47) KDM4EALDH1A1KMT2AMEN1CYP1A2
SCHEMBL203002 0.74 FFAR4 (0.44) KDM4EALDH1A1SMN1; SMN2TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9417477-B2 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-20150146140-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 US disclosed
US-7719644-B2 Optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2010-05-18 US disclosed
US-20090033835-A1 Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2009-02-05 US disclosed
US-20080284957-A1 Optical Resin Film, Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
WO-2006082818-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2006-08-10 WO disclosed
US-7008569-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-03-07 US disclosed
US-20040057141-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-03-25 US disclosed
EP-1395855-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-03-10 EP disclosed
WO-2002088784-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2002-11-07 WO disclosed