Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | PPARG | P37231 | 5/20 | 0.65 |
| ▸ | F7 | P08709 | 4/20 | 0.65 |
| ▸ | F3 | P13726 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | PPARD | Q03181 | 4/20 | 0.65 |
| ▸ | PPARA | Q07869 | 4/20 | 0.65 |
| ▸ | FABP3 | P05413 | 3/20 | 0.65 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.65 |
| ▸ | FABP4 | P15090 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.65 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24986050 | 1.00 | ALDH1A1 (0.65) | ALDH1A1PPARGF7F3KDM4E | |
| SCHEMBL24016792 | 0.98 | ALDH1A1 (0.62) | ALDH1A1PPARGF7F3KDM4E | |
| SCHEMBL31216417 | 0.94 | TERT (0.61) | PPARGF7F3PPARDPPARA | |
| Ammonia Solution, Strong SCHEMBL8935018 | 0.92 | TERT (0.59) | PPARGF7F3PPARDPPARA | |
| SCHEMBL10384713 | 0.90 | TERT (0.57) | PPARGF7F3PPARDPPARA | |
| SCHEMBL6782134 | 0.90 | TERT (0.57) | PPARGF7F3PPARDPPARA | |
| SCHEMBL8746647 | 0.90 | TERT (0.57) | PPARGF7F3PPARDPPARA | |
| SCHEMBL24637602 | 0.87 | ALDH1A1 (0.51) | ALDH1A1PPARGF7F3KDM4E | |
| SCHEMBL12071438 | 0.86 | ALDH1A1 (0.68) | ALDH1A1PPARGF7F3KDM4E | |
| SCHEMBL12179748 | 0.86 | ALDH1A1 (0.68) | ALDH1A1PPARGF7F3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11077197-B2 | Lipids and compositions for the delivery of therapeutics | ARBUTUS BIOPHARMA CORPORATION (CA) | 2021-08-03 | — | — | US | disclosed |
| US-20180092971-A1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11077197-B2 | Lipids and compositions for the delivery of therapeutics | SGMS2, APOB, MBOAT1 | ALDH1A1 4491/4885PPARG 860/4885F7 1027/4885 |
| US-20180092971-A1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | PHOSPHO1, SGMS2, MBOAT1 | ALDH1A1 4584/4885PPARG 849/4885F7 1206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.