Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 7/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19214219 | 0.80 | CHRNB2 (0.37) | CHRNB2CHRNA4CHRNB4CHRNA3ALDH1A1 | |
| SCHEMBL19107414 | 0.79 | MGAM (0.36) | CHRNB2CHRNA4ALDH1A1HSD17B10ALOX15 | |
| SCHEMBL20164264 | 0.79 | TSHR (0.38) | CHRNB2CHRNA4ALDH1A1LMNAHSD17B10 | |
| SCHEMBL17326989 | 0.79 | ALDH1A1 (0.39) | CHRNB2CHRNA4ALDH1A1SOAT1 | |
| SCHEMBL8146803 | 0.78 | CHRNB2 (0.36) | CHRNB2CHRNA4CHRNB4CHRNA3ALDH1A1 | |
| SCHEMBL25333041 | 0.78 | ALDH1A1 (0.37) | CHRNB2CHRNA4ALDH1A1LMNAHSD17B10 | |
| SCHEMBL29043851 | 0.78 | SMN1; SMN2 (0.35) | CHRNB2CHRNA4CHRNB4CHRNA3ALDH1A1 | |
| SCHEMBL9357927 | 0.77 | ALDH1A1 (0.42) | CHRNB2CHRNA4ALDH1A1LMNAHSD17B10 | |
| SCHEMBL20180238 | 0.77 | MGAM (0.41) | CHRNB2CHRNA4ALDH1A1LMNAHSD17B10 | |
| SCHEMBL28492886 | 0.77 | CHRNB2 (0.35) | CHRNB2CHRNA4ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10882924-B2 | Procatalyst for polymerization of olefins | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2021-01-05 | — | — | US | disclosed |
| US-20190225716-A1 | PROCATALYST FOR POLYMERIZATION OF OLEFINS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-07-25 | — | — | US | disclosed |
| WO-2018060406-A1 | PROCATALYST FOR POLYMERIZATION OF OLEFINS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2018-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10882924-B2 | Procatalyst for polymerization of olefins | PPOX, POR, OGFOD1 | CHRNB2 2796/4885CHRNA4 1850/4885CHRNB4 2110/4885 |
| US-20190225716-A1 | PROCATALYST FOR POLYMERIZATION OF OLEFINS | PPOX, POR, OGFOD1 | CHRNB2 2796/4885CHRNA4 1850/4885CHRNB4 2110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.