SCHEMBL200325

SCHEMBL200325

CCC(OC(=O)c1ccc(-c2ccccc2)cc1)C1CC2C=CC1C2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.47
CD274 Q9NZQ7 1/20 0.47
SMN1; SMN2 Q16637 4/20 0.38
MAPT P10636 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
SCN1A P35498 1/20 0.38
SCN2A Q99250 1/20 0.38
SCN3A Q9NY46 1/20 0.38
UTS2R Q9UKP6 1/20 0.37
SLC1A5 Q15758 1/20 0.37
KDM4E B2RXH2 1/20 0.36
HPGD P15428 2/20 0.36
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
KMT2A Q03164 1/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
TRPM8 Q7Z2W7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203801 0.84 PDCD1 (0.54) PDCD1CD274SMN1; SMN2MAPTSCN1A
SCHEMBL201540 0.74 PDCD1 (0.41) PDCD1CD274SMN1; SMN2MAPTALDH1A1
SCHEMBL32688720 0.72 EPHX2 (0.33) KDM4EALDH1A1
SCHEMBL2839505 0.72 SCN1A (0.47) PDCD1CD274SMN1; SMN2MAPTSCN1A
SCHEMBL200865 0.72 KDM4E (0.47) SMN1; SMN2SLC1A5KDM4EALDH1A1KMT2A
SCHEMBL32689045 0.71 KDM4E (0.33) KDM4EALDH1A1RAB9A
SCHEMBL203802 0.70 KDM4E (0.45) PDCD1CD274SMN1; SMN2SCN1ASCN2A
SCHEMBL25615625 0.70 PDCD1 (0.70) PDCD1CD274SMN1; SMN2MAPTL3MBTL1
SCHEMBL21525764 0.70 PTGS2 (0.41) KDM4EALDH1A1
SCHEMBL32688513 0.69 MGAM (0.40) KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9417477-B2 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-20150146140-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 US disclosed
US-7719644-B2 Optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2010-05-18 US disclosed
US-20090033835-A1 Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2009-02-05 US disclosed
US-20080284957-A1 Optical Resin Film, Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
WO-2006082818-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2006-08-10 WO disclosed
US-7008569-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-03-07 US disclosed
US-20040057141-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-03-25 US disclosed
EP-1395855-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-03-10 EP disclosed
WO-2002088784-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2002-11-07 WO disclosed