SCHEMBL203801

SCHEMBL203801

CC(OC(=O)c1ccc(-c2ccccc2)cc1)C1CC2C=CC1C2

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.54
CD274 Q9NZQ7 1/20 0.54
SCN1A P35498 2/20 0.40
SCN2A Q99250 2/20 0.40
SCN3A Q9NY46 2/20 0.40
SMN1; SMN2 Q16637 4/20 0.39
TRPM8 Q7Z2W7 1/20 0.39
FASN P49327 1/20 0.38
PTPRC P08575 1/20 0.37
PTPN2 P17706 1/20 0.37
PTPN1 P18031 1/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
UTS2R Q9UKP6 1/20 0.37
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
LMNA P02545 2/20 0.36
SLC1A5 Q15758 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL201540 0.89 PDCD1 (0.41) PDCD1CD274SMN1; SMN2NPC1RAB9A
SCHEMBL200325 0.84 PDCD1 (0.47) PDCD1CD274SCN1ASCN2ASCN3A
SCHEMBL200407 0.83 ADRB2 (0.40) SMN1; SMN2UTS2RNPC1RAB9AALDH1A1
SCHEMBL203248 0.83 SCN1A (0.46) SCN1ASCN2ASCN3ASMN1; SMN2PTPRC
SCHEMBL200629 0.76 POLB (0.41) UTS2RNPC1RAB9AALDH1A1HTT
SCHEMBL203302 0.76 ALDH1A1 (0.39) SMN1; SMN2PTPRCPTPN2PTPN1LMNA
SCHEMBL2839505 0.75 SCN1A (0.47) PDCD1CD274SCN1ASCN2ASCN3A
SCHEMBL17683882 0.73 PDCD1 (0.67) PDCD1CD274SCN1ASCN2ASCN3A
SCHEMBL21525764 0.72 PTGS2 (0.41) LMNAALDH1A1KDM4ECYP2D6
SCHEMBL200865 0.72 KDM4E (0.47) SMN1; SMN2LMNASLC1A5ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9417477-B2 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-20150146140-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 US disclosed
US-7719644-B2 Optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2010-05-18 US disclosed
US-20090033835-A1 Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2009-02-05 US disclosed
US-20080284957-A1 Optical Resin Film, Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
WO-2006098162-A1 OPTICAL COMPENSATION SHEET, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2006-09-21 WO disclosed
WO-2006082818-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2006-08-10 WO disclosed
US-7008569-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-03-07 US disclosed
US-20040057141-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-03-25 US disclosed
EP-1395855-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-03-10 EP disclosed
WO-2002088784-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2002-11-07 WO disclosed