SCHEMBL203802

SCHEMBL203802

O=C(OCCC1CC2C=CC1C2)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.45
SLC1A5 Q15758 1/20 0.42
TDP1 Q9NUW8 4/20 0.41
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PKM P14618 1/20 0.38
NPY1R P25929 1/20 0.38
NPY2R P49146 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
TSHR P16473 1/20 0.38
PDCD1 Q15116 1/20 0.38
CD274 Q9NZQ7 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
SCN1A P35498 1/20 0.37
SCN2A Q99250 1/20 0.37
SCN3A Q9NY46 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL200326 0.93 TDP1 (0.46) KDM4ESLC1A5TDP1ALDH1A1LMNA
SCHEMBL201541 0.89 NPC1 (0.41) KDM4ETDP1ALDH1A1SMN1; SMN2NPC1
SCHEMBL200865 0.87 KDM4E (0.47) KDM4ESLC1A5TDP1ALDH1A1LMNA
SCHEMBL15800079 0.86 ESR1 (0.48) KDM4ETDP1ALDH1A1LMNASMN1; SMN2
SCHEMBL18385917 0.85 ALDH1A1 (0.43) KDM4ETDP1ALDH1A1PKMESR1
SCHEMBL200408 0.83 HRH3 (0.48) KDM4ETDP1ALDH1A1LMNASMN1; SMN2
SCHEMBL203249 0.83 SCN1A (0.48) KDM4ETDP1ALDH1A1LMNAPKM
SCHEMBL14435505 0.79 PPM1B (0.47) KDM4ETDP1ALDH1A1PKMTSHR
SCHEMBL4403504 0.79 PPM1B (0.47) KDM4ETDP1ALDH1A1PKMTSHR
SCHEMBL12634161 0.79 TDP1 (0.52) KDM4ETDP1ALDH1A1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9417477-B2 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-20150146140-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 US disclosed
US-7719644-B2 Optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2010-05-18 US disclosed
US-20090033835-A1 Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2009-02-05 US disclosed
US-20080284957-A1 Optical Resin Film, Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
WO-2006098162-A1 OPTICAL COMPENSATION SHEET, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2006-09-21 WO disclosed
WO-2006082818-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2006-08-10 WO disclosed
US-7008569-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-03-07 US disclosed
US-20040057141-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-03-25 US disclosed
EP-1395855-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-03-10 EP disclosed
WO-2002088784-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2002-11-07 WO disclosed