SCHEMBL200326

SCHEMBL200326

O=C(OCCCC1CC2C=CC1C2)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.46
KDM4E B2RXH2 5/20 0.43
SLC1A5 Q15758 1/20 0.40
ALDH1A1 P00352 3/20 0.40
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
PKM P14618 1/20 0.37
NPY1R P25929 1/20 0.37
NPY2R P49146 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203802 0.93 KDM4E (0.45) TDP1KDM4ESLC1A5ALDH1A1LMNA
SCHEMBL200865 0.85 KDM4E (0.47) TDP1KDM4ESLC1A5ALDH1A1LMNA
SCHEMBL201541 0.82 NPC1 (0.41) TDP1KDM4EALDH1A1SMN1; SMN2
SCHEMBL15800079 0.79 ESR1 (0.48) TDP1KDM4EALDH1A1LMNASMN1; SMN2
SCHEMBL18385917 0.78 ALDH1A1 (0.43) TDP1KDM4EALDH1A1PKM
SCHEMBL10044814 0.77 ESR1 (0.42) KDM4ELMNASMN1; SMN2
SCHEMBL14435505 0.77 PPM1B (0.47) TDP1KDM4EALDH1A1PKM
SCHEMBL4403504 0.77 PPM1B (0.47) TDP1KDM4EALDH1A1PKM
SCHEMBL4400488 0.77 TDP1 (0.45) TDP1KDM4EALDH1A1LMNASMN1; SMN2
SCHEMBL203249 0.76 SCN1A (0.48) TDP1KDM4EALDH1A1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9417477-B2 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-20150146140-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 US disclosed
US-7719644-B2 Optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2010-05-18 US disclosed
US-20090033835-A1 Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2009-02-05 US disclosed
US-20080284957-A1 Optical Resin Film, Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
WO-2006082818-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2006-08-10 WO disclosed
US-7008569-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-03-07 US disclosed
US-20040057141-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-03-25 US disclosed
EP-1395855-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-03-10 EP disclosed
WO-2002088784-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2002-11-07 WO disclosed