Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435505 | 0.88 | PPM1B (0.47) | TDP1KDM4EALDH1A1KMT2APKM | |
| SCHEMBL4403504 | 0.88 | PPM1B (0.47) | TDP1KDM4EALDH1A1KMT2APKM | |
| SCHEMBL4403485 | 0.81 | KDM4E (0.35) | TDP1LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL417008 | 0.81 | POLB (0.43) | TDP1KDM4EALDH1A1KMT2APKM | |
| SCHEMBL14449086 | 0.81 | KDM4E (0.35) | TDP1LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL200865 | 0.81 | KDM4E (0.47) | TDP1LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL203802 | 0.79 | KDM4E (0.45) | TDP1LMNAKDM4EALDH1A1PKM | |
| SCHEMBL122602 | 0.78 | ALDH1A1 (0.41) | TDP1LMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL203002 | 0.78 | FFAR4 (0.44) | TDP1KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL10023890 | 0.78 | MAPT (0.46) | TDP1KDM4EALDH1A1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094760-B1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | 3M INNOVATIVE PROPERTIES CO (US) | 2017-05-31 | — | — | EP | disclosed |
| US-8431625-B2 | Compositions curable by ring opening metathesis polymerization at low temperatures and their application in the dental field | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-04-30 | — | — | US | disclosed |
| US-8178604-B2 | Solid materials obtainable by ring-opening metathesis polymerization | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178604-B2 | Solid materials obtainable by ring-opening metathesis polymerization | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-05-15 | — | — | US | disclosed |
| EP-1815838-B1 | Solid materials obtainable by the ring-opening methathesis polymerization | 3M INNOVATIVE PROPERTIES CO (US) | 2010-09-08 | — | — | EP | disclosed |
| US-20100036015-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | 3M INNOVATIVE PROPERTIES COMPANY | 2010-02-11 | — | — | US | disclosed |
| US-20100036015-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | 3M INNOVATIVE PROPERTIES COMPANY | 2010-02-11 | — | — | US | disclosed |
| US-20090088494-A1 | SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION | 3M INNOVATIVE PROPERTIES COMPANY | 2009-04-02 | — | — | US | disclosed |
| US-20090088494-A1 | SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION | 3M INNOVATIVE PROPERTIES COMPANY | 2009-04-02 | — | — | US | disclosed |
| EP-1942125-A1 | Compositions curable by ring opening metathesis polymerarization at low temperatures and their application in the dental field | 3M Innovative Properties Company (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2008077001-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-06-26 | — | — | WO | disclosed |
| WO-2007089801-A1 | SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-08-09 | — | — | WO | disclosed |
| EP-1815838-A1 | Solid materials obtainable by the ring-opening methathesis polymerization | 3M Innovative Properties Company (US) | 2007-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036015-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | DNMT3B, HMBS, MMAB | TDP1 1542/4885LMNA 3949/4885KDM4E 3465/4885 |
| US-20090088494-A1 | SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION | MMAB, DNMT3B, RHEB | TDP1 3862/4885LMNA 2576/4885KDM4E 1902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.