SCHEMBL20033366

SCHEMBL20033366

Cn1c2ccccc2c2cc(-c3cccc(-c4cccnc4)c3)ncc21

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 2/20 0.50
PIM1 P11309 6/20 0.44
PIM3 Q86V86 3/20 0.44
PIM2 Q9P1W9 3/20 0.44
CYP2A6 P11509 2/20 0.43
CYP2E1 P05181 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2B6 P20813 1/20 0.42
CYP2C19 P33261 1/20 0.42
BACE1 P56817 1/20 0.40
GPR3 P46089 1/20 0.40
GSK3B P49841 1/20 0.40
TOP2A P11388 1/20 0.40
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRA3 P34903 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20033220 0.85 CYP11B2 (0.56) CYP11B2PIM1CYP2A6GPR3GSK3B
SCHEMBL16625724 0.82 GPR3 (0.52) CYP11B2PIM1GPR3GSK3BGABRG2
SCHEMBL2721311 0.76 DRD2 (0.49) CYP11B2PIM1CYP2A6CYP2C9GSK3B
SCHEMBL19731916 0.75 TOP2A (0.42) CYP11B2GPR3TOP2A
SCHEMBL20033221 0.75 DRD2 (0.48) CYP11B2PIM1CYP2A6CYP2C9GSK3B
SCHEMBL20033222 0.74 CYP11B2 (0.46) CYP11B2PIM1CYP2A6CYP2E1CYP2C9
SCHEMBL20033223 0.74 CYP11B2 (0.46) CYP11B2PIM1CYP2C9GSK3BGABRG2
SCHEMBL12938257 0.74 GPR3 (0.48) PIM1PIM3PIM2GPR3TOP2A
SCHEMBL24299501 0.73 NPC1 (0.44) CYP11B2GPR3TOP2A
SCHEMBL22883537 0.73 TOP2A (0.46) CYP11B2GPR3TOP2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9941422-B2 Organic photoelectric conversion element and solar cell using the same Konica Minolta, Inc. (JP) 2018-04-10 US disclosed