Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18722102 | 0.84 | TDP1 (0.40) | SYKTDP1GLAHPGDAPEX1 | |
| SCHEMBL20034031 | 0.82 | ALDH1A1 (0.41) | SYKTDP1GLAHPGDAPEX1 | |
| SCHEMBL14160799 | 0.78 | ALDH1A1 (0.53) | TDP1GLAHPGDALDH1A1ATM | |
| SCHEMBL23072093 | 0.75 | POLB (0.41) | SYKTDP1GLAHPGDAPEX1 | |
| SCHEMBL16640327 | 0.73 | MAPT (0.43) | TDP1HPGDRECQLALDH1A1ATM | |
| SCHEMBL23072143 | 0.72 | ALDH1A1 (0.43) | SYKTDP1GLAHPGDAPEX1 | |
| SCHEMBL18376087 | 0.72 | TDP1 (0.45) | SYKTDP1GLAHPGDAPEX1 | |
| SCHEMBL18610705 | 0.72 | MAPT (0.42) | TDP1HPGDALDH1A1ATMMAPT | |
| SCHEMBL25752346 | 0.72 | MEN1 (0.50) | TDP1GLAALDH1A1ATMMAPT | |
| SCHEMBL23308322 | 0.71 | ATM (0.46) | SYKTDP1GLAHPGDAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9941479-B2 | Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-04-10 | — | — | US | disclosed |