Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 2/20 | 0.40 |
| ▸ | CDC25C | P30307 | 2/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23072091 | 0.87 | BCHE (0.43) | POLBHTTALDH1A1CDC25ACDC25C | |
| SCHEMBL14160799 | 0.81 | ALDH1A1 (0.53) | POLBHTTALDH1A1CDC25ACDC25C | |
| SCHEMBL18722102 | 0.80 | TDP1 (0.40) | POLBHTTALDH1A1CDC25ACDC25C | |
| SCHEMBL23308373 | 0.79 | HCRTR1 (0.49) | HTTALDH1A1TDP1SYKGLA | |
| SCHEMBL23072143 | 0.79 | ALDH1A1 (0.43) | POLBHTTALDH1A1PRKD3PRKCG | |
| SCHEMBL23072112 | 0.77 | POLB (0.40) | POLBHTTALDH1A1CDC25ACDC25C | |
| SCHEMBL28794093 | 0.76 | POLB (0.44) | POLBHTTALDH1A1CDC25ACDC25C | |
| SCHEMBL31170681 | 0.75 | MEN1 (0.51) | POLBHTTALDH1A1CDC25ACDC25C | |
| SCHEMBL25752346 | 0.75 | MEN1 (0.50) | POLBHTTALDH1A1CDC25ACDC25C | |
| SCHEMBL20034014 | 0.75 | SYK (0.43) | POLBHTTALDH1A1CDC25ACDC25C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230255101-A1 | Tetradentate Metal Complexes with Carbon Group Bridging Ligands | UNIV ARIZONA STATE (US) | 2023-08-10 | — | — | US | disclosed |
| US-20210126208-A1 | Tetradentate Metal Complexes with Carbon Group Bridging Ligands | UNIV ARIZONA STATE (US) | 2021-04-29 | — | — | US | disclosed |
| US-10944064-B2 | Tetradentate metal complexes with carbon group bridging ligands | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210126208-A1 | Tetradentate Metal Complexes with Carbon Group Bridging Ligands | STAU1, POLR1G, CLTC | POLB 390/4885HTT 3075/4885ALDH1A1 3464/4885 |
| US-10944064-B2 | Tetradentate metal complexes with carbon group bridging ligands | STAU1, POLR1G, CLTC | POLB 390/4885HTT 3075/4885ALDH1A1 3464/4885 |
| US-20230255101-A1 | Tetradentate Metal Complexes with Carbon Group Bridging Ligands | STAU1, POLR1G, CLTC | POLB 390/4885HTT 3075/4885ALDH1A1 3464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.