Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16334504 | 0.77 | CLK4 (0.56) | ALDH1A1PTGS2HPGDHDAC4HDAC2 | |
| SCHEMBL7647031 | 0.76 | PTGS2 (0.58) | TOP1ALDH1A1HSD17B10HTTPTGS1 | |
| SCHEMBL25522683 | 0.76 | KDM4E (0.54) | ALDH1A1HSD17B10HTTHPGDCYP2A6 | |
| SCHEMBL37278 | 0.74 | PTGS2 (0.66) | TOP1ALDH1A1HSD17B10HTTPTGS1 | |
| SCHEMBL15966197 | 0.74 | NOS3 (0.43) | ALDH1A1HSD17B10MAPK1NISCH | |
| SCHEMBL12854142 | 0.74 | PTGS2 (0.51) | TOP1ALDH1A1HSD17B10HTTPTGS1 | |
| SCHEMBL8285125 | 0.74 | DPP4 (0.47) | ALDH1A1HPGDCYP2A6 | |
| SCHEMBL7412828 | 0.74 | PTGS2 (0.59) | TOP1ALDH1A1HSD17B10HTTPTGS1 | |
| SCHEMBL8526461 | 0.73 | ALDH1A1 (0.50) | TOP1ALDH1A1HSD17B10HTTPTGS1 | |
| SCHEMBL12854073 | 0.73 | PTPRC (0.55) | TOP1ALDH1A1HSD17B10HTTPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117185993-A | Preparation and application of amide compound containing substituted benzene mercapto pyridine structural unit | 南通华祥医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-116806218-A | Sulfonamide and its use for the treatment of parasitic helminth infections and diseases | 新基公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-111517902-B | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-114144410-A | Polyarylurea derivatives and their use in the treatment of muscular diseases | 阿纳格纳斯生物技术股份有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-111517902-A | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2020-08-11 | — | — | CN | disclosed |
| US-9941479-B2 | Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-04-10 | — | — | US | disclosed |