Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29709996 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HPGDBCL2L1BACE1 | |
| SCHEMBL4400609 | 0.84 | ABL1 (0.47) | ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL2592408 | 0.83 | TDP1 (0.44) | ALDH1A1HDAC8HTTLMNAL3MBTL1 | |
| SCHEMBL2592406 | 0.83 | CYP2A6 (0.57) | ALDH1A1HSD17B10HPGDHTTPTGS2 | |
| SCHEMBL6871603 | 0.82 | CAMKK2 (0.56) | ALDH1A1BCL2L1 | |
| SCHEMBL8855211 | 0.81 | TDP1 (0.47) | PTGS1PTGS2 | |
| SCHEMBL14712123 | 0.81 | MEN1 (0.40) | ALDH1A1HSD17B10HPGDHTTMAPK1 | |
| SCHEMBL17593363 | 0.81 | MKNK1 (0.46) | ALDH1A1HSD17B10HTTL3MBTL1 | |
| SCHEMBL29594708 | 0.77 | RIPK1 (0.47) | ALDH1A1HSD17B10HPGDBCL2L1HDAC8 | |
| SCHEMBL28545758 | 0.77 | RIPK1 (0.47) | ALDH1A1HSD17B10HPGDBCL2L1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109355932-B | Low-temperature dyeing liquid for polyformaldehyde fibers and dyeing method thereof | 唐山开滦化工科技有限公司 | 2021-04-06 | — | — | CN | claimed |
| CN-109355932-A | A kind of the low temperature dyeing liquid and its colouring method of polyformaldehyde fibre | 唐山开滦化工科技有限公司 | 2019-02-19 | — | — | CN | claimed |
| CN-108281568-A | A kind of top emitting white light organic electroluminescent device and preparation method thereof | 吉林大学 | 2018-07-13 | — | — | CN | claimed |
| US-12612371-B2 | Sigma-1 receptor ligands and therapeutic uses thereof | UNIVERSITE DE STRASBOURG (FR) | 2026-04-28 | — | — | US | disclosed |
| EP-4076456-B1 | SIGMA-1 RECEPTOR LIGANDS AND THERAPEUTIC USES THEREOF | UNIV STRASBOURG (FR) | 2024-05-01 | — | — | EP | disclosed |
| CN-114686397-B | Method for preventing and controlling phytophthora camphorata | 南京林业大学 | 2023-08-01 | — | — | CN | disclosed |
| US-20230076057-A1 | SIGMA-1 RECEPTOR LIGANDS AND THERAPEUTIC USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2023-03-09 | — | — | US | disclosed |
| EP-4076456-A1 | SIGMA-1 RECEPTOR LIGANDS AND THERAPEUTIC USES THEREOF | Université de Strasbourg (FR) | 2022-10-26 | — | — | EP | disclosed |
| CN-114980891-A | Sigma-1 receptor ligands and therapeutic uses thereof | 斯特拉斯堡大学 | 2022-08-30 | — | — | CN | disclosed |
| WO-2021123174-A1 | SIGMA-1 RECEPTOR LIGANDS AND THERAPEUTIC USES THEREOF | UNIVERSITE DE STRASBOURG (FR) | 2021-06-24 | — | — | WO | disclosed |
| CN-109355932-B | Low-temperature dyeing liquid for polyformaldehyde fibers and dyeing method thereof | 唐山开滦化工科技有限公司 | 2021-04-06 | — | — | CN | disclosed |
| CN-102916134-A | Electron transfer layer, organic electroluminescent device with electron transfer layer and manufacturing method thereof | KUNSHAN VISIONOX DISPLAY TECH | 2013-02-06 | — | — | CN | disclosed |
| EP-0618889-B1 | TRI-SUBSTITUTED PHENYL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CELLTECH THERAPEUTICS LTD (GB) | 1998-12-30 | — | — | EP | disclosed |
| US-5626791-A | FERROELECTRIC LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | disclosed |
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |
| EP-0165753-B1 | HERBICIDAL THIOPHENESULFONAMIDES AND PYRIDINESULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-12-11 | — | — | EP | disclosed |
| US-4784684-A | Herbicidal pyridinesulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-15 | — | — | US | disclosed |
| US-4668279-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-05-26 | — | — | US | disclosed |
| EP-0165753-A2 | Herbicidal thiophenesulfonamides and pyridinesulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12612371-B2 | Sigma-1 receptor ligands and therapeutic uses thereof | SIGMAR1, OPRL1, OPRM1 | ALDH1A1 1484/4885HSD17B10 1647/4885HPGD 3619/4885 |
| US-20230076057-A1 | SIGMA-1 RECEPTOR LIGANDS AND THERAPEUTIC USES THEREOF | SIGMAR1, OPRL1, TMEM97 | ALDH1A1 1523/4885HSD17B10 1563/4885HPGD 3298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.