Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1194484 | 0.87 | ALDH1A1 (0.55) | GABRA1GABRB2TSHRALDH1A1TDP1 | |
| Phosphine SCHEMBL2238711 | 0.85 | ALDH1A1 (0.52) | GABRA1GABRB2TSHRALDH1A1TDP1 | |
| SCHEMBL545684 | 0.85 | ALDH1A1 (0.52) | GABRA1GABRB2TSHRALDH1A1TDP1 | |
| SCHEMBL18307741 | 0.83 | GABRA1 (0.44) | GABRA1GABRB2TSHRALDH1A1TDP1 | |
| SCHEMBL11020611 | 0.82 | ALDH1A1 (0.50) | GABRA1GABRB2TSHRALDH1A1TDP1 | |
| SCHEMBL10094721 | 0.82 | GABRA1 (0.42) | GABRA1GABRB2TSHRALDH1A1TDP1 | |
| SCHEMBL4748717 | 0.81 | GABRA1 (0.42) | GABRA1GABRB2TSHRALDH1A1TDP1 | |
| SCHEMBL2911757 | 0.81 | GABRA1 (0.68) | GABRA1GABRB2TSHRALDH1A1TDP1 | |
| SCHEMBL30407772 | 0.79 | GABRA1 (0.58) | GABRA1GABRB2TSHRALDH1A1TDP1 | |
| SCHEMBL5496813 | 0.79 | GABRA1 (0.58) | GABRA1GABRB2TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938253-B2 | Catalysts for efficient Z-selective metathesis | TRUSTEES OF BOSTON COLLEGE (US) | 2018-04-10 | — | — | US | disclosed |