Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11144108 | 0.87 | LMNA (0.44) | ALDH1A1CYP3A4MAPTPOLBSMN1; SMN2 | |
| SCHEMBL1263025 | 0.79 | ELANE (0.59) | TDP1MAPK1ALDH1A1CYP3A4TSHR | |
| SCHEMBL8975663 | 0.78 | TDP1 (0.48) | TDP1MAPK1ALDH1A1CYP3A4TSHR | |
| SCHEMBL12862164 | 0.78 | CA1 (0.55) | TDP1MAPK1ALDH1A1CYP3A4MAPT | |
| SCHEMBL28080298 | 0.78 | ESR2 (0.48) | ALDH1A1CYP3A4MAPTKDM4EGAA | |
| SCHEMBL10725365 | 0.78 | LMNA (0.60) | TDP1ALDH1A1CYP3A4TSHRTEAD4 | |
| SCHEMBL16417752 | 0.77 | SMN1; SMN2 (0.46) | ALDH1A1MAPTSMN1; SMN2KDM4ETHRB | |
| Ethylene SCHEMBL4257350 | 0.77 | LMNA (0.59) | TDP1MAPK1ALDH1A1CYP3A4MAPT | |
| SCHEMBL12644763 | 0.76 | NFE2L2 (0.39) | ALDH1A1SMN1; SMN2MAOAKDM4EHPGD | |
| SCHEMBL13893604 | 0.76 | KMT2A (0.43) | CYP3A4MAPTSMN1; SMN2MAOAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021219647-A1 | METHOD FOR THE CONTINUOUS SYNTHESIS OF PARACETAMOL | IPSOMEDIC (FR) | 2021-11-04 | — | — | WO | disclosed |
| EP-3305784-A1 | HAPTENS OF QUETIAPINE FOR USE IN IMMUNOASSAYS | Janssen Pharmaceutica NV (BE) | 2018-04-11 | — | — | EP | disclosed |